2-Bromomescaline

2-Bromomescaline (2-Br-M) is a derivative of the phenethylamine hallucinogen mescaline which has an unusual 2-bromo substitution.[1][2] It is an agonist for serotonin receptors, with a binding affinity of 215 nM at 5-HT1A, 513 nM at 5-HT2A and 379 nM at 5-HT2C, so while it is around ten times more tightly binding than mescaline at 5-HT1A and 5-HT2A receptors, it is over twenty times more potent at 5-HT2C.[3]

2-Bromomescaline
Clinical data
ATC code
  • none
Identifiers
PubChem CID
ChemSpider
Chemical and physical data
FormulaC11H16BrNO3
Molar mass290.153 g/mol g·mol−1
3D model (JSmol)

See also

References
  1. Alexander Shulgin; Tania Manning; Paul F Daley (2011). The Shulgin Index. Volume 1. Psychedelic Phenethylamines and Related Compounds. Transform Press. p. 280–281, 355. ISBN 978-0-9630096-3-0.
  2. Pecherer, B.; Sunbury, R. C.; Brossi, A. (June 1972). "A novel synthesis of aromatic methoxy and methylenedioxy substituted 2,3,4,5-tetrahydro-1H3-benzazepines". Journal of Heterocyclic Chemistry. 9 (3): 609–616. doi:10.1002/jhet.5570090322.
  3. Daniel Trachsel; David Lehmann; Christoph Enzensperger (2013). Phenethylamine Von der Struktur zur Funktion. Nachtschatten Verlag AG. p. 908–910. ISBN 978-3-03788-700-4.
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