PTI-2
PTI-2 is an indole-based synthetic cannabinoid.[1] It is one of few synthetic cannabinoids containing a thiazole group and is closely related to PTI-1. These compounds may be viewed as simplified analogues of indole-3-heterocycle compounds originally developed by Organon and subsequently further researched by Merck.[2][3][4][5]
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Formula | C23H33N3OS |
Molar mass | 399.60 g/mol g·mol−1 |
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References
- "PTI-2". Cayman Chemical. Retrieved 8 July 2015.
- Julia Adam-Worrall, et al. (Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor. Patent US 7700634, priority date 5 March 2004
- Paul David Ratcliffe, et al. Indole Derivatives. Patent US 7763732, priority date 24 August 2005
- Julia Adam, et al. Indole Derivatives. Patent WO 2008/101995, priority date 22 February 2007
- Takao Kiyoi, et al. Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists. Bioorganic & Medicinal Chemistry Letters 2011; 21(6):1748-1753. doi: 10.1016/j.bmcl.2011.01.082
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