Corbadrine

Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States,[1][2] (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).[3]

Corbadrine
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.113.606
Chemical and physical data
FormulaC9H13NO3
Molar mass183.204 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

Corbadrine is also a metabolite of the antihypertensive drug methyldopa,[4] and plays a role in its pharmacology and effects.

See also

References

  1. Dr. Ian Morton; I.K. Morton; Judith M. Hall (31 October 1999). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 164–. ISBN 978-0-7514-0499-9.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 275–. ISBN 978-3-88763-075-1.
  3. "DailyMed — Search results for levonordefrin". DailyMed. Retrieved 20 February 2016.
  4. Sjoerdsma, A; Vendsalu, A; Engelman, K; Watts, D (1 October 1963). "Studies on the Metabolism and Mechanism of Action of Methyldopa". Circulation. 28 (4): 492–502. doi:10.1161/01.CIR.28.4.492.
  • Nordefrin at the US National Library of Medicine Medical Subject Headings (MeSH)


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