HU-336
HU-336 is a strongly antiangiogenic compound, significantly inhibiting angiogenesis at concentrations as low as 300 nM. It inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of pro- and antiangiogenic cytokines and their receptors. HU-336 is highly effective against tumor xenografts in nude mice.[1]
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Formula | C21H28O3 |
Molar mass | 328.445 g/mol g·mol−1 |
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References
- Natalya M. Kogan; et al. (2006). "A Cannabinoid Quinone Inhibits Angiogenesis by Targeting Vascular Endothelial Cells". Molecular Pharmacology. 70 (1): 51–59. doi:10.1124/mol.105.021089. PMID 16571653.
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