AL-38022A
AL-38022A is an indazole derivative drug which is one of a range of similar drugs developed for scientific research and with some possible clinical applications. It acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around 4x less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests on animals, it fully substituted for both DOM and 5-MeO-DMT.[1]
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Formula | C13H17N3O |
Molar mass | 231.293 g/mol g·mol−1 |
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Melting point | 106 to 107 °C (223 to 225 °F) |
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References
- May, JA; Sharif, NA; Chen, HH; Liao, JC; Kelly, CR; Glennon, RA; Young, R; Li, JX; Rice, KC; France, CP (2009). "Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A (S)-2-(8,9-dihydro-7H-pyrano2,3-gindazol-1-yl)-1-methylethylamine". Pharmacology Biochemistry and Behavior. 91 (3): 307–14. doi:10.1016/j.pbb.2008.07.015. PMC 3763814. PMID 18718483.
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5-HT1 |
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5-HT2 |
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