MDPHP
MDPHP (3',4'-Methylenedioxy-α-pyrrolidinohexiophenone) is a stimulant of the cathinone class originally developed in the 1960s,[1] which has been reported as a novel designer drug. In the UK its slang name is monkey dust.[2] It is closely related to the potent stimulant MDPV though with slightly milder effects, and has been used as an alternative in some countries following the banning of MDPV.[3][4][5][6]
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Formula | C17H23NO3 |
Molar mass | 289.369 g/mol g·mol−1 |
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Legal Status
MDPHP is specifically listed as a controlled substance in Japan [7] and Hungary,[8] and is controlled under analogue provisions in a number of other jurisdictions.
See also
References
- Herbert, Koeppe; Karl, Zeile; Gerhard, Ludwig (28 May 1965), Patent DE1545591 - Verfahren zur Herstellung von α-Aminoketonen mit heterocyclischer Aminogruppe (in German)
- "Monkey Dust drug use 'an epidemic', emergency workers warn". BBC. 10 August 2018. Retrieved 16 August 2018.
- Zaitsu K, Katagi M, Tsuchihashi H, Ishii A. Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: a review of their pharmacology, acute toxicity, and metabolism. Forensic Toxicology 2014 Jan; 32(1):1-8. Zaitsu, Kei; Katagi, Munehiro; Tsuchihashi, Hitoshi; Ishii, Akira (2013). "Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: A review of their pharmacology, acute toxicity, and metabolism". Forensic Toxicology. 32: 1. doi:10.1007/s11419-013-0218-1.
- Kaizaki-Mitsumoto A, et al. Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market. Forensic Toxicology 2016 Jan; 34(1):108-114. Kaizaki-Mitsumoto, Asuka; Noguchi, Naoki; Yamaguchi, Saki; Odanaka, Yuki; Matsubayashi, Satoko; Kumamoto, Hiroki; Fukuhara, Kiyoshi; Funada, Masahiko; Wada, Kiyoshi; Numazawa, Satoshi (2015). "Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market". Forensic Toxicology. 34: 108. doi:10.1007/s11419-015-0293-6.
- Beck O, Bäckberg M, Signell P, Helander A. Intoxications in the STRIDA project involving a panorama of psychostimulant pyrovalerone derivatives, MDPV copycats. Clin Toxicol (Phila). 2017 Sep 12:1-8. Beck, O; Bäckberg, M; Signell, P; Helander, A (2017). "Intoxications in the STRIDA project involving a panorama of psychostimulant pyrovalerone derivatives, MDPV copycats". Clinical toxicology (Philadelphia, Pa.): 1–8. doi:10.1080/15563650.2017.1370097. PMID 28895757.
- Fowble KL, Shepard JRE, Musah RA. Identification and classification of cathinone unknowns by statistical analysis processing of direct analysis in real time-high resolution mass spectrometry-derived "neutral loss" spectra. Talanta. 2018 Mar 1;179:546-553. Fowble, K. L; Shepard, J. R. E; Musah, R. A (2018). "Identification and classification of cathinone unknowns by statistical analysis processing of direct analysis in real time-high resolution mass spectrometry-derived "neutral loss" spectra". Talanta. 179: 546–553. doi:10.1016/j.talanta.2017.11.020. PMID 29310273.
- "指定薬物名称・構造式一覧(平成27年9月16日現在)" (PDF) (in Japanese). 厚生労働省. 16 September 2015. Retrieved 8 October 2015.
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