MDPHP

MDPHP (3',4'-Methylenedioxy-α-pyrrolidinohexiophenone) is a stimulant of the cathinone class originally developed in the 1960s,[1] which has been reported as a novel designer drug. In the UK its slang name is monkey dust.[2] It is closely related to the potent stimulant MDPV though with slightly milder effects, and has been used as an alternative in some countries following the banning of MDPV.[3][4][5][6]

3',4'-Methylenedioxy-α-pyrrolidinohexiophenone
Legal status
Legal status
  • UK: Class B
  • Illegal in Japan and Hungary
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC17H23NO3
Molar mass289.369 g/mol g·mol−1
3D model (JSmol)

MDPHP is specifically listed as a controlled substance in Japan [7] and Hungary,[8] and is controlled under analogue provisions in a number of other jurisdictions.

See also

References
  1. Herbert, Koeppe; Karl, Zeile; Gerhard, Ludwig (28 May 1965), Patent DE1545591 - Verfahren zur Herstellung von α-Aminoketonen mit heterocyclischer Aminogruppe (in German)
  2. "Monkey Dust drug use 'an epidemic', emergency workers warn". BBC. 10 August 2018. Retrieved 16 August 2018.
  3. Zaitsu K, Katagi M, Tsuchihashi H, Ishii A. Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: a review of their pharmacology, acute toxicity, and metabolism. Forensic Toxicology 2014 Jan; 32(1):1-8. Zaitsu, Kei; Katagi, Munehiro; Tsuchihashi, Hitoshi; Ishii, Akira (2013). "Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: A review of their pharmacology, acute toxicity, and metabolism". Forensic Toxicology. 32: 1. doi:10.1007/s11419-013-0218-1.
  4. Kaizaki-Mitsumoto A, et al. Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market. Forensic Toxicology 2016 Jan; 34(1):108-114. Kaizaki-Mitsumoto, Asuka; Noguchi, Naoki; Yamaguchi, Saki; Odanaka, Yuki; Matsubayashi, Satoko; Kumamoto, Hiroki; Fukuhara, Kiyoshi; Funada, Masahiko; Wada, Kiyoshi; Numazawa, Satoshi (2015). "Three 25-NBOMe-type drugs, three other phenethylamine-type drugs (25I-NBMD, RH34, and escaline), eight cathinone derivatives, and a phencyclidine analog MMXE, newly identified in ingredients of drug products before they were sold on the drug market". Forensic Toxicology. 34: 108. doi:10.1007/s11419-015-0293-6.
  5. Beck O, Bäckberg M, Signell P, Helander A. Intoxications in the STRIDA project involving a panorama of psychostimulant pyrovalerone derivatives, MDPV copycats. Clin Toxicol (Phila). 2017 Sep 12:1-8. Beck, O; Bäckberg, M; Signell, P; Helander, A (2017). "Intoxications in the STRIDA project involving a panorama of psychostimulant pyrovalerone derivatives, MDPV copycats". Clinical toxicology (Philadelphia, Pa.): 1–8. doi:10.1080/15563650.2017.1370097. PMID 28895757.
  6. Fowble KL, Shepard JRE, Musah RA. Identification and classification of cathinone unknowns by statistical analysis processing of direct analysis in real time-high resolution mass spectrometry-derived "neutral loss" spectra. Talanta. 2018 Mar 1;179:546-553. Fowble, K. L; Shepard, J. R. E; Musah, R. A (2018). "Identification and classification of cathinone unknowns by statistical analysis processing of direct analysis in real time-high resolution mass spectrometry-derived "neutral loss" spectra". Talanta. 179: 546–553. doi:10.1016/j.talanta.2017.11.020. PMID 29310273.
  7. "指定薬物名称・構造式一覧（平成27年9月16日現在）" (PDF) (in Japanese). 厚生労働省. 16 September 2015. Retrieved 8 October 2015.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.