Morazone

Morazone (Novartrina, Orsimon, Rosimon-Neu, Tarcuzate) is a nonsteroidal anti-inflammatory drug (NSAID), originally developed by the German pharmaceutical company Ravensberg in the 1950s, which is used as an analgesic.[1][2][3] It produces phenmetrazine as a major metabolite and has been reported to have been abused as a recreational drug in the past.[4][5][6][7]

Morazone
Clinical data
Routes of
administration		Oral, SC, IM[1]
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.026.771
Chemical and physical data
FormulaC23H27N3O2
Molar mass377.48 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

See also


References
  1. Seyffart, G. (1991). Drug dosage in Renal Insufficiency. Boston: Kluwer Academic Publishers. p. 399. ISBN 978-0-7923-0964-2.
  2. US patent 2943022, Siemer, H. & Doppstadt, A., "Substituted 1-phenyl-2,3-dimethyl-4-morpholino methyl pyrazolone-(5) Compounds and Process of Making Same", issued 1960-06-28, assigned to Ravensberg
  3. J. Buckingham, ed. (1996). Dictionary of Organic Compounds. 7. London: Chapman & Hall. p. 4659. ISBN 978-0-412-54090-5.
  4. Bohn, G.; Rücker, G.; Kröger, H. (1976). "Investigations of the decomposition and detection of morazone by thin-layer- and gas-liquid-chromatography". Archives of Toxicology. 35 (3): 213–220. doi:10.1007/bf00293569. PMID 989292.
  5. Neugebauer, M. (1984). "Some new urinary metabolites of famprofazone and morazone in man". Journal of Pharmaceutical and Biomedical Analysis. 2 (1): 53–60. doi:10.1016/0731-7085(84)80089-8. PMID 16867765.
  6. Kingreen, J. C.; Breger, G. (1984). "Pellagra in morazone abuse". Zeitschrift für Hautkrankheiten. 59 (9): 573–577. PMID 6145264.
  7. Daunderer, M.; Janzen, W. (1972). "Rosimon-NEU--a non-prescription analgesic on the adolescent drug scene". Beiträge zur Gerichtlichen Medizin. 29: 138–143. PMID 5081964.
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