Hexacyclonate

Hexacyclonate (Gevilon) is a stimulant drug. It has been used for the treatment of alcoholism[1] and for increasing motivation in elderly patients,[2] but is now mainly used for the treatment of hyperlipoproteinaemia. [3][4] It is chemically similar to the anticonvulsant gabapentin, with a hydroxyl group replacing the amine.

Hexacyclonate
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC9H16O3
Molar mass172.222 g·mol−1
3D model (JSmol)
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The latter use may be incorrectly assigned, as "Gevilon" has been used as a trade name for gemfibrozil, a well-known drug for dislypidemia.

References
  1. Chesrow, EJ; Sabatini, R; Musci, JP; Kaplitze, SE; Marquardt, GH (May 1962). "Adjunctive treatment of the chronic alcoholic with hexacyclonate sodium". Illinois Medical Journal (121): 546–548.
  2. Morrison BO. Pharmaco-motivation of the geriatric patient: a preliminary report on hexacyclonate. Journal of the Louisiana State Medical Society. 1962 Jan;114:23-6.
  3. Milewicz A, Plamieniak Z, Bohdanowicz-Pawlak A. Therapeutic effect of gevilon in patients with hyperlipoproteinaemia. Polish Journal of Medicine and Pharmacy. 1992 Apr-Jun;24(2):91-5.
  4. Gazdikova K, Korecka P, Springer V, Gazdik F. Pharmacoeconomic aspects of patients treated by hemodialysis. Bratislavske Lekarske Listy. 2003;104(10):329-34.


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