Piperacetazine

Piperacetazine
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
	IUPAC name 1-[10-[3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl]phenothiazin-2-yl]ethanone;
PubChem CID	19675;
ChemSpider	18533;
UNII	KL6248WNW4;
ChEMBL	ChEMBL1584 ;
CompTox Dashboard (EPA)	DTXSID7023481 ;
ECHA InfoCard	100.021.194
Chemical and physical data
Formula	C24H30N2O2S
Molar mass	410.57219 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)c1ccc2Sc3ccccc3N(CCCN4CCC(CCO)CC4)c2c1;
	InChI InChI=InChI=1S/C24H30N2O2S/c1-18(28)20-7-8-24-22(17-20)26(21-5-2-3-6-23(21)29-24)13-4-12-25-14-9-19(10-15-25)11-16-27/h2-3,5-8,17,19,27H,4,9-16H2,1H3; Key:BTFMCMVEUCGQDX-UHFFFAOYSA-N;

Piperacetazine (Quide) is an antipsychotic prodrug, most notably used for schizophrenia.[1]

References

Rada, R. T; Donlon, P. T (1974). "Piperacetazine in ambulatory chronic schizophrenic patients". Current Therapeutic Research. 16 (2): 124–9. PMID 4156665.

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[1] Rada, R. T; Donlon, P. T (1974). "Piperacetazine in ambulatory chronic schizophrenic patients". Current Therapeutic Research. 16 (2): 124–9. PMID 4156665.

Antipsychotics (N05A)
Typical	Butyrophenones: Benperidol Bromperidol Droperidol Haloperidol^# Moperone Pipamperone Spiperone Timiperone Trifluperidol Diphenylbutylpiperidines: Fluspirilene Penfluridol Pimozide Phenothiazines: Acetophenazine Butaperazine Carphenazine (carfenazine)^‡ Chlorpromazine Cyamemazine Dixyrazine Fluphenazine Levomepromazine (methotrimeprazine) Mesoridazine Perazine Periciazine Perphenazine Piperacetazine Pipotiazine Prochlorperazine Promazine Sulforidazine Thiopropazate Thioproperazine Thioridazine Trifluoperazine Triflupromazine Thioxanthenes: Chlorprothixene Clopenthixol Flupentixol Tiotixene (thiothixene) Zuclopenthixol
Disputed	Benzamides: Amisulpride Levosulpiride Nemonapride Remoxipride^‡ Sulpiride Sultopride Tiapride Veralipride^‡ Butyrophenones: Melperone Tricyclics: Carpipramine Clocapramine Clorotepine Clotiapine Loxapine Mosapramine Others: Molindone
Atypical	Benzisoxazole/benzisothiazoles: Iloperidone Lurasidone Paliperidone Paliperidone palmitate Perospirone Risperidone^# Ziprasidone Butyrophenones: Lumateperone^† Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine^† Brexpiprazole Cariprazine Tricyclics: Asenapine Clozapine^# Olanzapine Quetiapine Zotepine Others: Blonanserin Pimavanserin Sertindole
Others	Azacyclonol Cannabidiol Oxypertine Reserpine Tetrabenazine
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III