Eticlopride

Eticlopride
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide;
CAS Number	97612-24-3 ;
PubChem CID	57267;
IUPHAR/BPS	966;
ChemSpider	51626 ;
UNII	J8M468HBH4;
ChEMBL	ChEMBL8946 ;
CompTox Dashboard (EPA)	DTXSID9048435 ;
Chemical and physical data
Formula	C17H25ClN2O3
Molar mass	340.845 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl;
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Eticlopride is a selective dopamine antagonist that acts on D₂ dopamine receptor. It is primarily used in pharmacological research.[1][2][3][4]

References

"Eticlopride hydrochloride".
Renee Claytora, Joshua A. Lilea, 1, Michael A. Nader (2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys". Pharmacology Biochemistry and Behavior. 83 (3): 456–464. doi:10.1016/j.pbb.2006.03.007. PMID 16631246.CS1 maint: multiple names: authors list (link)
Hemby, Scott; Smith, James; Dworkin, Steven (1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats". The Journal of Pharmacology and Experimental Therapeutics. 277 (3): 1247–1258. PMID 8667185.
Haile, Colin; Kosten, Therese (2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats". The Journal of Pharmacology and Experimental Therapeutics. 299 (2): 509–518. PMID 11602661.

Eticlopride at the US National Library of Medicine Medical Subject Headings (MeSH)

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