Estradiol cypionate/testosterone enanthate

Estradiol cypionate/testosterone enanthate (EC/TE), sold under the brand name Supligol, is an injectable combination medication of estradiol cypionate (EC), an estrogen, and testosterone enanthate (TE), an androgen/anabolic steroid, which is used in menopausal hormone therapy for women, to treat prostatic hypertrophy in men, to treat osteoporosis, and to suppress lactation in women, among other uses.[1][2] It contains 4 mg EC and 80 mg TE (57.5 mg free testosterone) in oil solution in each ampoule and is administered by intramuscular injection once every 3 to 6 weeks for hormone therapy in women.[1] The medication was marketed by 1976[1] and remains available today in Paraguay.[2]

Androgen replacement therapy formulations and dosages used in women
RouteMedicationMajor brand namesFormDosage
OralTestosterone undecanoateAndriol, JatenzoCapsule40–80 mg 1x/1–2 days
MethyltestosteroneMetandren, EstratestTablet0.5–10 mg/day
FluoxymesteroneHalotestinTablet1–2.5 mg 1x/1–2 days
NormethandroneaGinecosideTablet5 mg/day
TiboloneLivialTablet1.25–2.5 mg/day
Prasterone (DHEA)b–Tablet10–100 mg/day
SublingualMethyltestosteroneMetandrenTablet0.25 mg/day
TransdermalTestosteroneIntrinsaPatch150–300 μg/day
AndroGelGel, cream1–10 mg/day
VaginalPrasterone (DHEA)IntrarosaInsert6.5 mg/day
InjectionTestosterone propionateaTestovironOil solution25 mg 1x/1–2 weeks
Testosterone enanthateDelatestryl, Primodian DepotOil solution25–100 mg 1x/4–6 weeks
Testosterone cypionateDepo-Testosterone, Depo-TestadiolOil solution25–100 mg 1x/4–6 weeks
Testosterone isobutyrateaFemandren M, FolivirinAqueous suspension25–50 mg 1x/4–6 weeks
Mixed testosterone estersClimacteronaOil solution150 mg 1x/4–8 weeks
Omnadren, SustanonOil solution50–100 mg 1x/4–6 weeks
Nandrolone decanoateDeca-DurabolinOil solution25–50 mg 1x/6–12 weeks
Prasterone enanthateaGynodian DepotOil solution200 mg 1x/4–6 weeks
ImplantTestosteroneTestopelPellet50–100 mg 1x/3–6 months
Notes: Premenopausal women produce about 230 ± 70 μg testosterone per day (6.4 ± 2.0 mg testosterone per 4 weeks), with a range of 130 to 330 μg per day (3.6–9.2 mg per 4 weeks). Footnotes: a = Mostly discontinued or unavailable. b = Over-the-counter. Sources: See template.
Not to be confused with Estradiol cypionate/testosterone cypionate or Supligol NF.
Estradiol cypionate /
testosterone enanthate
Combination of
Estradiol cypionateEstrogen
Testosterone enanthateAndrogen; Anabolic steroid
Clinical data
Trade namesSupligol
Other namesEC/TE
Routes of
administration		Intramuscular injection

See also

References
  1. Vademecum de bolsillo: guía de especialidades medicinales : con índice terapéutico actualizado (enfermedades y síntomas de urgencia). Editorial Celcius - J.J. Vallory. 1976. SUPLIGOL (Ampollas) Comp. Testosterona enantato 80 mg (-= Testosterona 57,5 mg) y Estradiol ciclopentil-propionato, 4 mg. — Indic. Climaterio y sus trastornos, hipertrofia de la próstata, osteoporosis, supresión de la lactancia, etc. — Doslf. Climaterio: 1 ampolla por via I.M. cada 3-6 semanas, segun el caso. Osteoporosis: 1 ampolla cada 3 semanas. Supresion de la lactancia: 1 ampolla despues del parto.
  2. https://www.drugs.com/international/supligol.html



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