Methandriol dipropionate

Methandriol dipropionate (MADP), also known as methylandrostenediol dipropionate and sold under the brand names Arbolic, Durabolic, Or-Bolic, Probolik, and Protabolin among others, is a synthetic, injected anabolic-androgenic steroid (AAS) and a 17α-alkylated derivative of 5-androstenediol.[2][1] It is an androgen ester – specifically, the C3,17β dipropionate ester of methandriol (17α-methyl-5-androstenediol) – and acts as a prodrug of methandriol in the body.[2][1] Methandriol dipropionate is administered by intramuscular injection and, relative to methandriol, has an extended duration via this route of several days due to a depot effect afforded by its ester.[1] It was marketed in the United States,[2] but is no longer available in this country.[3]

Methandriol dipropionate
Clinical data
Trade namesArbolic, Durabolic, Or-Bolic, Probolik, Protabolin
Other namesMethylandrostenediol dipropionate; MADP; 17α-Methylandrost-5-ene-3,17-diol 3,17β-dipropionate
Routes of
administration		Intramuscular injection[1]
Drug classAndrogen; Anabolic steroid; Androgen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ECHA InfoCard100.020.669
Chemical and physical data
FormulaC26H40O4
Molar mass416.602 g·mol−1
3D model (JSmol)

See also

References
  1. William Llewellyn (1 November 2008). Anabolics: Anabolic Steroid Reference Guide. William Llewellyn. pp. 294–296. ISBN 978-0-9679304-7-3.
  2. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 663–. ISBN 978-3-88763-075-1.
  3. "Drugs@FDA: FDA Approved Drug Products". United States Food and Drug Administration. Retrieved 29 November 2016.



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