ZM-182345

ZM-182345 is a nonsteroidal progestin that was never marketed.[1][2] It was derived from structural modification of the nonsteroidal antiandrogen hydroxyflutamide.[1][2] ZM-182345 was found to be at least as potent as progesterone as a progestogen in animals but to also possess androgenic activity.[1]

ZM-182345
Identifiers
PubChem CID
Chemical and physical data
FormulaC19H16F6N2O4
Molar mass450.337 g·mol−1
3D model (JSmol)

References

  1. Dukes M, Furr BJ, Hughes LR, Tucker H, Woodburn JR (2000). "Nonsteroidal progestins and antiprogestins related to flutamide". Steroids. 65 (10–11): 725–31. doi:10.1016/s0039-128x(00)00179-3. PMID 11108883.
  2. Eckhard Ottow; Hilmar Weinmann (8 September 2008). Nuclear Receptors as Drug Targets. John Wiley & Sons. pp. 209–. ISBN 978-3-527-62330-3.



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