Drupanol

Drupanol is a naturally occurring phenol that has been isolated from the seeds of Psoralea drupaceae.[1][2] Although drupanol is sometimes said to be the same compound as bakuchiol, the two compounds are in fact distinct; they have the same molecular formula and weight but different chemical structures and hence are structural isomers.[1] Bakuchiol has been found to possess antiandrogenic activity in vitro.[3]

Drupanol
Identifiers
CAS Number
Chemical and physical data
FormulaC18H24O
Molar mass256.389 g·mol−1
3D model (JSmol)

References
  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 120,473. ISBN 978-1-4757-2085-3.
  2. Golovina, L. A.; Nikonov, G. K. (1973). "The structure of drupanol — A new phenol from Psoralea drupaceae". Chemistry of Natural Compounds. 9 (1): 7–9. doi:10.1007/BF00580876. ISSN 0009-3130.
  3. Miao, L., Ma, S. W., Fan, G. W., Wang, H., Wang, Y. F., & Chai, L. J. (2013). Bakuchiol inhibits the androgen induced-proliferation of prostate cancer cell line LNCaP through suppression of AR transcription activity. Tianjin Journal of Traditional Chinese Medicine, 5, 012.


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