Methylclostebol

Methylclostebol, also known as 4-chloro-17α-methyltestosterone or as 4-chloro-17α-methylandrost-4-en-17β-ol-3-one, is a synthetic, orally active anabolic-androgenic steroid (AAS) and designer steroid that has been sold on the Internet as a "dietary supplement",[1][2] but it has never been studied for medical use.[3] It is the 17α-alkylated variant of clostebol (4-chlorotestosterone).[4]

Methylclostebol
Clinical data
Other namesChloromethyltestosterone; CMT; 4-Chloro-17α-methyltestosterone; 4-Chloro-17α-methylandrost-4-en-17β-ol-3-one
Routes of
administration
Oral
Legal status
Legal status
  • US: Schedule III
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
Chemical and physical data
FormulaC20H29ClO2
Molar mass336.90 g·mol−1
3D model (JSmol)

German athletes used methylclostebol as a performance enhancing drug in the 1960s and 1970s,[3] and it is currently banned by the World Anti-Doping Agency.[5]

See also

References

  1. Rahnema CD, Crosnoe LE, Kim ED (2015). "Designer steroids - over-the-counter supplements and their androgenic component: review of an increasing problem". Andrology. 3 (2): 150–5. doi:10.1111/andr.307. PMID 25684733.
  2. Pope HG, Wood RI, Rogol A, Nyberg F, Bowers L, Bhasin S (2014). "Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement". Endocr. Rev. 35 (3): 341–75. doi:10.1210/er.2013-1058. PMC 4026349. PMID 24423981.
  3. Rahnema, C. D.; Crosnoe, L. E.; Kim, E. D. (2015). "Designer steroids - over-the-counter supplements and their androgenic component: Review of an increasing problem". Andrology. 3 (2): 150. doi:10.1111/andr.307. PMID 25684733.
  4. Lootens, L., Van Eenoo, P., Pozo Mendoza, O. J., Meulemans, P., Leroux-Roels, G., & Delbeke, F. (2010). Application of in vivo urinary steroid detection in uPA+/+-SCID chimeric mice. In 28th Cologne workshop on Dope Analysis (Manfred Donike workshop) (Vol. 18, pp. 52-61). Sportverlag Strauss.
  5. "World Anti-Doping Code: International Standard Prohibited List" (PDF). January 2017.
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