Estradiol valerate/dienogest
Estradiol valerate/dienogest (EV/DNG), sold under the brand names Lafamme, Natazia and Qlaira among others, is a combination product of estradiol valerate, an estrogen, and dienogest, a progestogen, which is used in menopausal hormone therapy in and as a birth control pill to prevent pregnancy in women. It is taken by mouth.
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Combination of | |
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Estradiol valerate | Estrogen |
Dienogest | Progestogen |
Clinical data | |
Trade names | Lafamme, Natazia, Qlaira |
Other names | EV/DNG; SH T00658ID; Bay 86-5027; BAY86-5027 |
Routes of administration | By mouth |
Drug class | Estrogen; Progestogen |
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Birth control pills containing EV/DNG are associated with a significantly increased risk of venous thromboembolism.[1] However, they are associated with a significantly lower risk of venous thromboembolism than birth control pills containing ethinylestradiol and a progestin.[1]
See also
References
- Fruzzetti F, Cagnacci A (2018). "Venous thrombosis and hormonal contraception: what's new with estradiol-based hormonal contraceptives?". Open Access J Contracept. 9: 75–79. doi:10.2147/OAJC.S179673. PMC 6239102. PMID 30519125.
Progestogens (and progestins) |
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ER |
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GPER |
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PR |
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