Chlormadinone caproate

Chlormadinone caproate (CMC) is a progestin and a progestogen ester which was studied for potential use in combined injectable contraceptives but was never marketed.[1][2][3][4] It was assessed in combination with estradiol valerate at doses of 80 mg and 3 mg, respectively.[1][2][3] In addition to chlormadinone acetate (CMA), analogues of CMC include gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone caproate, megestrol caproate, and methenmadinone caproate.

Not to be confused with Chlormadinone acetate.
Chlormadinone caproate
Clinical data
Other namesCMC; Chlormadinone hexanoate; 6-Chloro-17α-hydroxy-Δ6-progesterone hexanoate; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione hexanoate
Routes of
administration		Intramuscular injection
Drug classProgestogen; Progestin; Progestogen ester
Identifiers
CAS Number
Chemical and physical data
FormulaC27H37ClO4
Molar mass461.040 g/mol g·mol−1
3D model (JSmol)

See also

References
  1. Daniel R. Mishell (1983). Long-acting Steroid Contraception. Raven Press. pp. 69, 77. ISBN 978-0-89004-932-7.
  2. Toppozada MK (April 1994). "Existing once-a-month combined injectable contraceptives". Contraception. 49 (4): 293–301. doi:10.1016/0010-7824(94)90029-9. PMID 8013216.
  3. Newton JR, D'arcangues C, Hall PE (1994). "A review of "once-a-month" combined injectable contraceptives". J Obstet Gynaecol (Lahore). 4 Suppl 1: S1–34. doi:10.3109/01443619409027641. PMID 12290848.
  4. Bopp RJ, Murphy HW, Nash JF, Novotny CR (September 1972). "GLC determination of chlormadinone acetate in plasma". J Pharm Sci. 61 (9): 1441–4. doi:10.1002/jps.2600610919. PMID 4115914.



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