Mestranol/norethisterone

Mestranol/norethisterone (brand names Norethin, Noriday, Norinyl, Norquen, Ortho-Novum, others) is a combination of the estrogen ethinylestradiol and the progestin norethisterone (norethindrone) which was introduced in 1963 and was the second combined oral contraceptive to be marketed, following mestranol/noretynodrel in 1960.[1] Although most mestranol-containing oral contraceptive formulations have been discontinued, the combination remains available today in the United States in a single formulation under the brand name Norinyl 1+50 28-Day.[2] It has largely been superseded by ethinylestradiol/norethisterone, which has been marketed under many of the same brand names.[3][4]

Not to be confused with Mestranol/noretynodrel.
Mestranol/norethisterone
Combination of
MestranolEstrogen
NorethisteroneProgestogen
Clinical data
Trade namesNorethin, Noriday, Norinyl, Norquen, Ortho-Novum, others
AHFS/Drugs.comMonograph
Pregnancy
category
  • US: X (Contraindicated)
    Routes of
    administration    		By mouth
    Legal status
    Legal status

    See also

    References
    1. Lara Marks (2010). Sexual Chemistry: A History of the Contraceptive Pill. Yale University Press. pp. 74, 76. ISBN 978-0-300-16791-7.
    2. "Drugs@FDA: FDA Approved Drug Products". United States Food and Drug Administration. Retrieved 22 December 2016.
    3. Robert W. Blum (22 October 2013). Adolescent Health Care: Clinical Issues. Elsevier Science. pp. 216–. ISBN 978-1-4832-7738-7.
    4. Helen Varney; Jan M. Kriebs; Carolyn L. Gegor (2004). Varney's Midwifery. Jones & Bartlett Learning. pp. 515–. ISBN 978-0-7637-1856-5.



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