Nandrolone cyclohexanecarboxylate

Nandrolone cyclohexanecarboxylate
Clinical data
Trade names	Nor-Durandron, Norlongandron
Other names	NSC-3351; Nandrolone hexahydrobenzoate; 19-Nortestosterone 17β-cyclohexanecarboxylate
Routes of; administration	Intramuscular injection
Drug class	Androgen; Anabolic steroid; Androgen ester; Progestogen
Identifiers
	IUPAC name [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] cyclohexanecarboxylate;
CAS Number	18470-94-5;
PubChem CID	9929986;
ChemSpider	8105617;
UNII	45FAH33FMM;
Chemical and physical data
Formula	C25H36O3
Molar mass	384.552 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)C4CCCCC4)CCC5=CC(=O)CC[C@H]35;
	InChI InChI=1S/C25H36O3/c1-25-14-13-20-19-10-8-18(26)15-17(19)7-9-21(20)22(25)11-12-23(25)28-24(27)16-5-3-2-4-6-16/h15-16,19-23H,2-14H2,1H3/t19-,20+,21+,22-,23-,25-/m0/s1; Key:AQMOXBCKEKPDRF-YNFNDHOQSA-N;

Nandrolone cyclohexanecarboxylate (brand names Nor-Durandron, Norlongandron; former developmental code name NSC-3351), or nandrolone hexahydrobenzoate, also known as 19-nortestosterone 17β-cyclohexanecarboxylate, is a synthetic androgen and anabolic steroid and a nandrolone ester that has been marketed by Ferring Pharmaceuticals since at least 1961.[1][2][3][4][5]

Relative affinities (%) of nandrolone and related steroids
Compound	PR	AR	ER	GR	MR	SHBG	CBG
Nandrolone	20	154–155	<0.1	0.5	1.6	1–16	0.1
Testosterone	1.0–1.2	100	<0.1	0.17	0.9	19–82	3–8
Estradiol	2.6	7.9	100	0.6	0.13	8.7–12	<0.1
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PR, testosterone for the AR, estradiol for the ER, dexamethasone for the GR, aldosterone for the MR, dihydrotestosterone for SHBG, and cortisol for CBG. Sources: See template.

References

J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 660–. ISBN 978-1-4757-2085-3.
Ashraf Mozayani; Lionel Raymon (15 October 2003). Handbook of Drug Interactions: A Clinical and Forensic Guide. Springer Science & Business Media. pp. 501–. ISBN 978-1-59259-654-6.
Cynthia A. Challener (1 December 2001). Chiral Drugs. Wiley. p. 131. ISBN 978-0-566-08411-9.
E. Buchborn; H. Jahrmärker; H.J. Karl; G.A. Martini; W. Müller; G. Riecker; H. Schwiegk; W. Siegenthaler; W. Stich (2 July 2013). Therapie innerer Krankheiten. Springer-Verlag. pp. 409–. ISBN 978-3-662-10489-7.
Svenska läkartidningen. Sveriges Läkarförbund. 1961. p. 1961.

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[Elks2014-1] J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 660–. ISBN 978-1-4757-2085-3.

[MozayaniRaymon2003-2] Ashraf Mozayani; Lionel Raymon (15 October 2003). Handbook of Drug Interactions: A Clinical and Forensic Guide. Springer Science & Business Media. pp. 501–. ISBN 978-1-59259-654-6.

[Challener2001-3] Cynthia A. Challener (1 December 2001). Chiral Drugs. Wiley. p. 131. ISBN 978-0-566-08411-9.

[BuchbornJahrmärker2013-4] E. Buchborn; H. Jahrmärker; H.J. Karl; G.A. Martini; W. Müller; G. Riecker; H. Schwiegk; W. Siegenthaler; W. Stich (2 July 2013). Therapie innerer Krankheiten. Springer-Verlag. pp. 409–. ISBN 978-3-662-10489-7.

[Läkarförbund1961-5] Svenska läkartidningen. Sveriges Läkarförbund. 1961. p. 1961.

Nandrolone cyclohexanecarboxylate

See also

References