Centalun

Centalun was developed by Boehringer Ingelheim in 1962[1] and is a psycholeptic drug with hypnotic and sedative effects, via allosteric agonism of the GABAA receptor.[2] It was previously used for sedation in medical procedures such as surgery,[3] orthopedics[4] and gynecology,[5] although it is no longer in clinical use. Despite its history of clinical use, centalun was never incorporated into the CSA and therefore remains unregulated as a drug of abuse.

Centalun
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: unscheduled
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC11H12O2
Molar mass176.212 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

References
  1. BE Patent 618130 'Procédé pour l'obtention d'alkinediols'
  2. Janke, W.; Glathe, H. (1964). "Experimental Studies on the Psychic Effect of Sedatives Under Normal and Stress Conditions". Psychologische Forschung. 27: 377–402. PMID 14233519.
  3. Monecke, K. (1964). "Pre- and Postoperative Use of Centalun in Surgery". Deutsches medizinisches Journal. 15: 470–471. PMID 14238754.
  4. Bruckschen, E. (1964). "Sedative Therapy with Centalun in Orthopedics". Deutsches medizinisches Journal. 15: 493–494. PMID 14243120.
  5. Gerlach, W.; Gerlach, E. (1964). "Experiences with Centalun in Obstetrical and Gynecological Patients". Medizinische Monatsschrift. 18: 131–133. PMID 14193290.
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