Cinolazepam
Cinolazepam[2] (marketed under the brand name Gerodorm)[3] is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as a hypnotic.
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| Trade names | Gerodorm |
| AHFS/Drugs.com | cinolazepam |
| Routes of administration | Oral |
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| Bioavailability | 90–100% |
| Metabolism | Hepatic |
| Elimination half-life | 3.8 hours[1] |
| Excretion | Renal |
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| Formula | C18H13ClFN3O2 |
| Molar mass | 357.8 g·mol−1 |
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| Chirality | Racemic mixture |
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It was patented in 1978 and came into medical use in 1992.[4] Cinolazepam is not approved for sale in the United States or Canada.
References
- "ZUSAMMENFASSUNG DER MERKMALE DES ARZNEIMITTELS" (Press release). (in Austrian German). Austria: G.L. Pharma GmbH. Bundesamt für Sicherheit im Gesundheitswesen. October 2018. Archived from the original on 2019-01-02. Retrieved 2019-01-02.
- US Patent 4388313 Novel 3-hydroxy-1,4-benzodiazepine-2-ones and process for the preparation thereof
- Lannacher Romania (1999). "Gerodorm". Produse Gerot inregistrate in Romania (in Romanian). Archived from the original on 11 October 2006. Retrieved 17 August 2006.
- Fischer, Jnos; Ganellin, C. Robin (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 530. ISBN 9783527607495.
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