Aprobarbital

Aprobarbital (or aprobarbitone), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.

Aprobarbital
Clinical data
Other namesaprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
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ATC code
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Identifiers
CAS Number
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ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.908
Chemical and physical data
FormulaC10H14N2O3
Molar mass210.23 g/mol g·mol−1
3D model (JSmol)
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See also: Alphenal

References
  1. Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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