Alphenal
Alphenal (Alphenal, Efrodal, Prophenal, Sanudorm), also known as 5-allyl-5-phenylbarbituric acid, is a barbiturate derivative developed in the 1920s.[1] It has primarily anticonvulsant properties, and was used occasionally for the treatment of epilepsy or convulsions, although not as commonly as better known barbiturates such as phenobarbital.[2][3] [4][5]
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Other names | 5-Phenyl-5-allylbarbituric acid |
Routes of administration | Oral |
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ECHA InfoCard | 100.003.718 |
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Formula | C13H12N2O3 |
Molar mass | 244.246 g/mol g·mol−1 |
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LD50: Mouse (Oral): 280 mg/kg
References
- DE Patent 526854
- Carissimi M, Nuovi Barbiturici Alogenati. Farmaco. Ediozione scientifica. 17(6):390-413. (1962).
- Martin, J. R.; Godel, T.; Hunkeler, W.; Jenck, F.; Moreau, J.-L.; Sleight, A. J.; Widmer, U. (2000). "Psychopharmacological Agents". doi:10.1002/0471238961.1619250313011820.a01. Cite journal requires
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(help) - Hans Brandenberger; Robert A. A. Maes (1997). Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists. Walter de Gruyter. p. 348. ISBN 978-3-11-010731-9. Retrieved 19 May 2012.
- Pelayo Camps García; Santiago Vázquez Cruz; Carmen Escolano Mirón (28 January 2005). Fundamentos de síntesis de fármacos. Edicions Universitat Barcelona. p. 161. ISBN 978-84-475-2876-9. Retrieved 19 May 2012.
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