Proxibarbital

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and in contrast to most barbiturates almost without hypnotic action.[1]

Proxibarbital
Clinical data
Other namesProxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
ECHA InfoCard100.018.004
Chemical and physical data
FormulaC10H14N2O4
Molar mass226.229 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

It was also used in the treatment of migraine headaches in a similar manner to butalbital.[2]

Valofane isomerises to Proxibarbal in vivo.

References

  1. Zajdel, P.; Kulig, K.; Zejc, A. (2008). Zejc, A.; Gorczyca, M. (eds.). Chemia leków, podręcznik dla studentów farmacji i farmaceutów (in Polish). Warszawa, Poland. ISBN 978-83-200-3652-7.
  2. Sulman, F. G.; Pfeifer, Y.; Tal, E. (1976). "Migraine therapy by enzyme induction with proxibarbital". Therapie der Gegenwart (in German). 115 (12): 2088–2103. PMID 14412.



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