List of psychedelic drugs

The following is a list of psychedelic drugs of various classes. Serotonergic psychedelics are usually considered to be the classical psychedelics, whereby the other classes are often only considered to have secondary psychedelic properties. Some of these compounds may be classified differently or under several categories, due to unique structural classification, multiple mechanisms of action, or to the fact that the precise pharmacodynamic actions of psychedelic drugs are not yet completely understood. Also, due to the vast amount of possible substitutions and analogs of psychedelic compounds, their total number is quite large and is not fully reflected within this list, leaving room for many that have not yet been sufficiently investigated and even others that have not yet been discovered.

Entries marked with a '#' are naturally occurring compounds.

Serotonergic psychedelics (serotonin 5-HT_2A receptor agonists)

Indoles
- Tryptamines [more specifically: alkylated tryptamines]
  - Psilocin #, also known as '4-HO-DMT'; another active constituent of the psilocybe genus of mushrooms; also a metabolite of psilocybin & psilacetin
  - Psilocybin #, also known as '4-PO-DMT'; the primary active constituent of the psilocybe genus of mushrooms; its effects are partially attributed to psilocin, to which it is a pro-drug via dephosphorylation
  - Bufotenin #, also known as '5-HO-DMT' & 'Dimethylserotonin'; another constituent of the skin & venom of psychoactive toads; its psychedelic activity is disputed; also a metabolite of 5-MeO-DMT
  - Baeocystin #, also known as '4-PO-NMT'; another active constituent of the psilocybe genus of mushrooms; its psychedelic activity is disputed
  - Aeruginascin #, also known as '4-PO-N-TMT', an active constituent of the mushroom Inocybe aeruginascens.
  - 5-MeO-DMT #, the primary active constituent of the skin & venom of psychoactive toads, a pro-drug to bufotenin via demethylation
  - N,N-Dimethyltryptamine #, also known as 'DMT'; the primary active constituent of the Amerindian brew Ayahuasca; endogenously present in various plants and animals, including humans, possibly a trace amine neurotransmitter
  - 5-Bromo-DMT #, was found in the marine invertebrates Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida
  - N-Methyl-N-ethyltryptamine, also known as 'MET'
  - N-Methyl-N-isopropyltryptamine, also known as 'MiPT'
  - N-Methyl-N-propyltryptamine, also known as MPT
  - N,N-Diethyltryptamine, also known as 'DET'
  - N-Ethyl-N-isopropyltryptamine, also known as 'EiPT'
  - N-Methyl-N-butyltryptamine, also known as 'MBT'
  - N-Propyl-N-isopropyltryptamine, also known as 'PiPT'
  - N,N-Dipropyltryptamine, also known as 'DPT'
  - N,N-Diisopropyltryptamine, also known as 'DiPT'
  - N,N-Diallyltryptamine, also known as 'DALT'
  - N,N-Dibutyltryptamine, also known as 'DBT'
  - N-Ethyltryptamine, also known as 'NET'
  - N-Methyltryptamine #, also known as 'NMT'; its psychedelic activity is disputed
  - Trimethyltryptamine, also known as 'TMT' (2,N,N-TMT, 5,N,N-TMT, & 7,N,N-TMT)
  - α-Methyltryptamine, also known as 'αMT' & 'AMT'; also has entactogenic properties
  - α-Ethyltryptamine, also known as 'αET' & 'AET'; also has entactogenic properties
  - α,N-DMT
  - α,N,N-Trimethyltryptamine, also known as 'α-TMT'
  - Ethocybin, also known as '4-PO-DET', 'CEY-19', & 'CEY-39'
  - 4-HO-MET, also known as 'Metocin', 'Methylcybin', & 'Colour'
  - 4-HO-DET, also known as 'Ethocin' & 'CZ-74'
  - 4-HO-MPT, also known as 'Meprocin'
  - 4-HO-MiPT, also known as 'Miprocin'
  - 4-HO-MALT
  - 4-HO-DPT, also known as 'Deprocin'
  - 4-HO-DiPT, also known as 'Iprocin'
  - 4-HO-DALT, also known as 'Daltocin'
  - 4-HO-DBT
  - 4-HO-DSBT
  - 4-HO-αMT
  - 4-HO-MPMI, also known as 'Lucigenol'
  - 4-HO-1,N,N-TMT, also known as '1-Me-4-HO-DMT', '1-methylpsilocin'
  - 4-HO-5-MeO-DMT, also known as 'Psilomethoxin'
  - 4-AcO-DMT, also known as 'Psilacetin'; its effects are partially attributed to psilocin, to which it is a pro-drug via deacetylation
  - 4-AcO-MET, also known as 'Metacetin'
  - 4-AcO-MiPT
  - 4-AcO-MALT
  - 4-AcO-DET, also known as 'Ethacetin'
  - 4-AcO-EiPT, also known as 'Ethipracetin'
  - 4-AcO-DPT, also known as 'Depracetin'
  - 4-AcO-DiPT, also known as 'Ipracetin'
  - 4-AcO-DALT, also known as 'Daltacetin'
  - 4-MeO-DMT
  - 4-MeO-MiPT
  - 5-MeO-NMT #,
  - 5-MeO-MET
  - 5-MeO-MPT
  - 5-MeO-MiPT, also known as 'Moxy'; also has entactogenic properties
  - 5-MeO-MALT
  - 5-MeO-DET
  - 5-MeO-EiPT
  - 5-MeO-EPT
  - 5-MeO-PiPT
  - 5-MeO-DPT
  - 5-MeO-DiPT, also known as 'Foxy Methoxy'
  - 5-MeO-DALT
  - 5-MeO-αMT, also has entactogenic properties
  - 5-MeO-αET, also has entactogenic properties
  - 5-MeO-MPMI
  - 5-MeO-2,N,N-TMT , also known as 'Indomethacin' & 'Indapex'
  - 5-MeO-7,N,N-TMT
  - 5-MeO-a,N-DMT, also known as 'α,N,O-TMS'
  - 4-F-5-MeO-DMT
  - 5-MeS-DMT
  - 5-Me-MiPT, its psychedelic activity is disputed
  - 5-HO-DiPT
  - 2-α-DMT
  - 2-Me-DET
  - 4-Me-αMT
  - 4-Me-αET, also has entactogenic properties
  - 7-Me-αET, also has entactogenic properties
  - 4,5-DHP-AMT, also known as 'AL-37350A'
  - 4,5-DHP-DMT
  - 4,5-MDO-DMT
  - 4,5-MDO-DiPT
  - 5,6-MDO-DiPT
  - 5,6-MDO-MiPT
  - 5-Fluoro-αMT, also has entactogenic properties
  - 6-Fluoro-αMT
  - 6-Fluoro-DMT
  - N,N-Tetramethylenetryptamine, also known as 'Pyr-T'
  - 4-HO-pyr-T
  - 5-MeO-pyr-T
  - RU-28306, also known as '4,a-Methylene-N,N-DMT'
  - O-4310, also known as '6-Fluoro-1-Isopropyl-4-HO-DMT'
  - CP-132,484, also known as '4,5-DHP-1-Methyltryptamine'
- Benzofuran derivatives (technically not tryptamines)
  - Dimemebfe, also known as '5-MeO-BFE'
  - 5-MeO-DiBF
- Ibogoids (can be classified as complex tryptamines)
  - Ibogaine #, the primary active constituent of iboga rootbark; also has dissociative properties
  - Voacangine #, another active constituent of iboga rootbark
- Ergolines [more specifically: Lysergamides] (can be classified as complex tryptamines, also contain a phenethylamine backbone)
  - Lysergic acid diethylamide, also known as 'LSD' & 'Acid'
  - Lysergic acid amide #, also known as 'LSA' & 'Ergine'; the primary active constituent of morning glory and Hawaiian baby woodrose seeds
  - N1-Methyl-lysergic acid diethylamide, also known as 'MLD-41'
  - N-Acetyl-lysergic acid diethylamide, also known as 'ALD-52'
  - 1-Propionyl-lysergic acid diethylamide, also known as '1P-LSD'; its effects are partially attributed to LSD, to which it is a pro-drug via hydrolyzation
  - 6-Allyl-6-nor-lysergic acid diethylamide, also known as 'AL-LAD'
  - 6-Butyl-6-nor-lysergic acid diethylamide, also known as 'BU-LAD'
  - 6-Ethyl-6-nor-lysergic acid diethylamide, also known as 'ETH-LAD'
  - 1-Propionyl-6-Ethyl-6-nor-lysergic acid diethylamide, also known as '1P-ETH-LAD'
  - 6-Propyl-6-nor-lysergic acid diethylamide, also known as 'PRO-LAD'
  - 6-Cyclopropyl-6-nor-lysergic acid diethylamide, also known as 'CYP-LAD'
  - 6-nor-Lysergic acid diethylamide, also known as 'PARGY-LAD'
  - Lysergic acid ethylamide, also known as 'LAE-32'
  - Lysergic acid α-hydroxyethylamide #, also known as 'LSH' & 'LAH'; another active constituent of morning glory seeds; an active constituent of some species of fungi
  - Lysergic acid 2-butyl amide, also known as 'LSB'
  - Lysergic acid 3-pentyl amide, also known as 'LSP'
  - Lysergic acid methyl ester, also known as 'LSME'
  - Lysergic acid 2,4-dimethylazetidide, also known as 'LSZ' & 'LA-SS-Az'
  - Lysergic acid piperidine, also known as 'LSD-Pip'; its psychedelic activity is disputed
  - N,N-Dimethyl-lysergamide, also known as 'DAM-57'
  - Methylisopropyllysergamide, also known as 'MIPLA'
  - N,N-Diallyllysergamide, also known as 'DAL'
  - N-Pyrrolidyllysergamide, also known as 'LPD-824'
  - N-Morpholinyllysergamide, also known as 'LSM-775'
  - 1-methyl-lysergic acid butanolamide, also known as 'Methysergide'; the active constituent of Sansert & Deseril; a pro-drug, has to be metabolized to methylergometrine to become psychoactive
  - Lysergic acid β-propanolamide #, also known as 'Ergonovine' & 'Ergometrine'; another active constituent of morning glory seeds; an active constituent of ergot fungi
  - Lysergic acid 1-butanolamide #, also known as 'Methylergonovine', 'Methergine', & 'Methylergometrine'; another active constituent of morning glory seeds; another active constituent of ergot fungi
Phenethylamines [more specifically: alkoxylated phenethylamines]
- Substituted phenethylamines
  - Mescaline #, the primary active constituent of certain cacti, such as peyote and San Pedro
  - Lophophine #, also known as 'MMDPEA'; another active constituent of certain cacti, such as peyote and San Pedro; also has entactogenic properties
  - Isomescaline
  - Cyclopropylmescaline
  - Thioisomescaline (2-TIM, 3-TIM, & 4-TIM)
  - 4-Desoxymescaline
  - Jimscaline
  - Escaline
  - Metaescaline
  - Thiometaescaline (3-TME, 4-TME, & 5-TME)
  - Trisescaline
  - Thiotrisescaline (3-T-TRIS & 4-T-TRIS)
  - Symbescaline
  - Asymbescaline
  - Thiosymbescaline (3-TSB & 4-TSB)
  - Phenescaline
  - Allylescaline, also known as 'AL'
  - Methallylescaline
  - Proscaline
  - Isoproscaline
  - Metaproscaline
  - Thioproscaline
  - Buscaline
  - Thiobuscaline
  - α-ethylmescaline, also known as 'AEM'
  - Ariadne, also known as 'α-Et-DOM', '4C-D', & 'Dimoxamine'
  - Macromerine
  - MEPEA
  - TOM (2-TOM & 5-TOM)
  - Bis-TOM
  - TOMSO, also known as '2-methoxy-4-methyl-5-methylsulfinylamphetamine'
  - TOET (2-TOET & 5-TOET)
  - BOH
  - BOM, also known as 'β-Methoxy-mescaline'
  - β-D
  - 4-D
  - DME
  - F-2
  - F-22
  - FLEA, also known as 'MDHMA'
  - MDPH
  - MDMP
  - Propynyl
  - 2C family (2,5-dimethoxy, 4-substituted phenethylamines)
    - βk-2C-B
    - 2C-B
    - 2CB-2EtO
    - 2CB-5EtO
    - 2CB-diEtO
    - 2C-B-FLY
    - 2C-B-BUTTERFLY
    - 2C-C
    - 2C-D
    - 2CD-2EtO
    - 2CD-diEtO
    - 2CD-5EtO
    - 2C-E
    - 2C-EF
    - 2C-F
    - 2C-G (2C-G-1, 2C-G-2, 2C-G-3, 2C-G-4, 2C-G-5, 2C-G-6, & 2C-G-N)
    - 2C-H
    - 2C-I
    - 2CI-2EtO
    - 2C-iP
    - 2C-N
    - 2C-O
    - 2C-O-4
    - 2C-P
    - 2C-SE
    - 2C-T
    - 2CT-5EtO
    - 2C-T-2
    - 2CT-2-2EtO
    - 2CT-2-5EtO
    - 2CT-2-diEtO
    - 2C-T-4 (2C-T-4 & Ψ-2C-T-4)
    - 2CT-4-2EtO
    - 2C-T-7
    - 2CT-7-2EtO
    - 2C-T-8
    - 2C-T-9
    - 2C-T-13
    - 2C-T-15
    - 2C-T-16
    - 2C-T-17
    - 2C-T-19,
    - 2C-T-21
    - 2C-TFM
    - 2C-YN
    - BOB, also known as 'β-Methoxy-2C-B'
    - BOD, also known as 'β-Methoxy-2C-D'
    - BOHD, also known as 'β-Hydroxy-2C-D'
    - HOT-2
    - HOT-7
    - HOT-17
    - Indane derivatives (technically not phenethylamines)
      - 2CB-Ind
    - Benzocyclobutene derivatives (technically not phenethylamines)
      - 2C-BCB, also known as 'TCB-2'
    - NBOMe derivatives
      - NBOMe-mescaline
      - 2C-H-NBOMe, also known as '25H-NBOMe'
      - 2C-C-NBOMe, also known as '25C-NBOMe'
      - 2CBCB-NBOMe, also known as 'NBOMe-TCB-2'
      - 2CBFly-NBOMe, also known as 'Cimbi-31'
      - 2C-B-NBOMe, also known as '25B-NBOMe', 'M25B-NBOMe', 'BOM 2-CB', 'Cimbi-36', 'Nova' or 'New Nexus'
      - 2C-I-NBOMe, also known as '25I-NBOMe', Cimbi-5, "Solaris" or "N-Bomb"
      - 2C-TFM-NBOMe, also known as '25TFM-NBOMe'
      - 2C-D-NBOMe, also known as '25D-NBOMe'
      - 2C-G-NBOMe, also known as '25G-NBOMe'
      - 2C-E-NBOMe, also known as '25E-NBOMe'
      - 2C-P-NBOMe, also known as '25P-NBOMe'
      - 2C-iP-NBOMe, also known as '25iP-NBOMe'
      - 2C-CN-NBOMe, also known as '25CN-NBOMe'
      - 2C-N-NBOMe, also known as '25N-NBOMe'
      - 2C-T-NBOMe, also known as '25T2-NBOMe'
      - 2C-T-4-NBOMe, also known as '25T4-NBOMe'
      - 2C-T-7-NBOMe, also known as '25T7-NBOMe'
      - DMBMPP, 2-Benzylpiperidine analogue of 25B-NBOMe
    - NBOH derivatives
      - 2C-C-NBOH, also known as '25C-NBOH' & 'NBOH-2CC'
      - 2C-B-NBOH, also known as '25B-NBOH'
      - 2C-I-NBOH, also known as '25I-NBOH'
      - 2C-CN-NBOH, also known as '25CN-NBOH' & 'NBOH-2C-CN'
    - NBMD derivatives
      - 2C-I-NBMD, also known as '25I-NBMD'
    - NBF derivatives
      - 2C-C-NBF, also known as '25C-NBF'
      - 2C-B-NBF, also known as '25B-NBF'
      - 2C-I-NBF, also known as '25I-NBF'
- Substituted amphetamines (alpha-methyl-phenethylamines)
  - 3C family (3,5-dimethoxy, 4-substituted amphetamines)
    - 3C-E
    - 3C-P
    - 3C-DFE
    - 3C-BZ
  - DOx family (2,5-dimethoxy, 4-substituted amphetamines)
    - DOAM
    - DOB
    - Meta-DOB
    - Methyl-DOB
    - DOBU
    - DOC
    - DOEF
    - DOET, also known as 'DOE'
    - DOI
    - DOM, also known as 'STP'
    - Ψ-DOM
    - DON
    - DOPR
    - DOiPR
    - DOT, also known as 'Aleph' (Aleph-2, Aleph-4, Aleph-6, & Aleph-7)
    - Meta-DOT
    - Ortho-DOT
    - DOTFM
  - Phenylcyclopropylamine derivatives (technically not amphetamines)
    - DMCPA
  - DMMDA
  - DMMDA-2
  - 2,5-dimethoxy-3,4-dimethylamphetamine, also known as 'Ganesha'; (G-3, G-4, G-5, & G-N)
  - 4-methyl-2,5-dimethoxymethamphetamine, also known as 'Beatrice', 'MDO-D', & 'MDOM'
  - 2,N-dimethyl-4,5-methylenedioxyamphetamine, also known as 'Madam-6'
  - Dimethoxyamphetamine (2,4-DMA, 2,5-DMA, & 3,4-DMA)
  - Trimethoxyamphetamine (TMA-2, TMA-6)
  - Tetramethoxyamphetamine
  - Br-DragonFLY
  - TFMFly
  - 2-Bromo-4,5-methylenedioxyamphetamine
  - 4-Bromo-3,5-dimethoxyamphetamine
  - EEE
  - EEM
  - EME
  - EMM
  - EDMA
  - EIDA
  - Ethyl-J, also known as 'EBDB'
  - Methyl-J, also known as 'MDMB'
  - Ethyl-K, also known as 'EBDP'
  - Methyl-K, also known as 'MBDP' & 'UWA-91'
  - IDNNA
  - Iris
  - MDAI
  - MDMAI
  - MDAT
  - MDMAT
  - MDAL
  - MDBU
  - MDBZ
  - MDDM
  - MDIP
  - MDMEOET
  - MDMEO
  - MDOH, also known as 'MDH'
  - MDHOET
  - MDPL
  - MDCPM
  - MDPR
  - MEDA
  - MEM
  - Methyl-DMA
  - MMDA, also known as '3-methoxy-MDA'; (2T-MMDA-3a & 4T-MMDA-2)
  - MMDA-2
  - 5-Methyl-MDA
  - MEE
  - MME
  - MPM
  - DiFMDA
  - 5-APB
  - 6-APB, also known as 'Benzofury'
  - 5-APDB
  - 6-APDB
  - 5-MAPB
  - 5-MAPDB
  - 6-MAPDB, its psychedelic activity is disputed
  - 6-MAPB
  - 6-EAPB
  - 5-EAPB
  - Para-Methoxyamphetamine, also known as 'PMA' & '4-MA'
  - Paramethoxymethamphetamine, also known as 'PMMA', 'Methyl-MA' & '4-MMA'
  - 4-Ethylamphetamine, also known as '4-EA'
  - 3-Methoxy-4-methylamphetamine, also known as 'MMA'
  - 4-Methylmethamphetamine, also known as '4-MMA'
  - 4-Methylthioamphetamine, also known as '4-MTA'
  - 4-Fluoroamphetamine, also known as '4-FA', 'PAL-303', 'Flux', 'Flits', 'R2D2', & 'Miley'
  - Norfenfluramine, also known as '3-TFMA'
  - Para-Iodoamphetamine, also known as 'PIA', '4-iodoamphetamine', & '4-IA'
  - Para-Chloroamphetamine, also known as 'PCA', '4-chloroamphetamine', & '4-CA'
Benzoxazines [more specifically: cyclopropylethynylated benzoxazines]
- Substituted benzoxazines
  - Efavirenz, the active constituent of Sustiva, Stocrin, & Efavir

Empathogens/entactogens (serotonin (5-HT) releasing agents)

Substituted methylenedioxy-phenethylamines (MDxx)
- MDMA, also known as 'Ecstasy', 'Molly', & 'Mandy'
- MDA, also known as 'Sass'
- 2,3-MDA, also known as 'ORTHO-MDA'
- 5-Methyl-MDA
- MMDA, also known as '3-methoxy-MDA'
- MDEA, also known as 'MDE'
- MBDB
- MDAL
- MDBU
- MDBZ
- MDDM
- MDIP
- MDMEOET
- MDMEO
- MDOH, also known as 'MDH'
- MDHOET
- MDPL
- MDCPM
- MDPR
- BDB, also known as 'MDB' & 'J'
- MMDA-2
- DiFMDA
- EIDA
- Ethyl-K, also known as 'EBDP'
- Lophophine #, also known as 'MMDPEA'; an active constituent of certain cacti, such as peyote and San Pedro
Substituted amphetamines (exclusively; most of the substituted methylenedioxy-phenethylamines also overlap this category)
- EDMA
- Para-Methoxyamphetamine, also known as 'PMA'
- Paramethoxymethamphetamine, also known as 'PMMA' & 'Methyl-MA'
- 4-Ethylamphetamine, also known as '4-EA'
- 3-Methoxy-4-methylamphetamine, also known as 'MMA'
- 4-Methylmethamphetamine, also known as '4-MMA'
- 4-Methylthioamphetamine, also known as '4-MTA'
- 4-Fluoroamphetamine, also known as '4-FA', 'PAL-303', 'Flux', 'Flits', 'R2D2', & 'Miley'
- Norfenfluramine, also known as '3-TFMA'
- Para-Iodoamphetamine, also known as 'PIA', '4-iodoamphetamine', & '4-IA'
- Para-Chloroamphetamine, also known as 'PCA', '4-chloroamphetamine', & '4-CA'
Substituted cathinones
- Methylone, also known as 'bk-MDMA' & 'MDMC'
- Ethylone, also known as 'bk-MDEA' & 'MDEC'
- Eutylone, also known as 'bk-EBDB'
- Butylone, also known as 'bk-MBDB'
- Pentylone, also known as 'bk-Methyl-K' & 'bk-MBDP'
- 4-Ethylmethcathinone, also known as '4-EMC'
Substituted benzofurans
- 5-APB
- 6-APB
- 5-APDB
- 6-APDB
- 5-MAPB
- 5-MAPDB
- 6-MAPDB, its psychedelic activity is disputed
- 6-MAPB
- 5-EAPB
- 6-EAPB
- 5-MBPB
Substituted tetralins
- MDAT
- MDMAT
- 6-CAT
- Tetralinylaminopropane, also known as 'TAP' & '6-APT'
Substituted indanes
- Trifluoromethylaminoindane, also known as 'TAI'
- Ethyltrifluoromethylaminoindane, also known as 'ETAI'
- 5-Iodo-2-aminoindane, also known as '5-IAI'
- MMAI
- MDAI
- MDMAI
- Indanylaminopropane, also known as '5-APDI' & 'IAP'
Substituted napthalenes
- Naphthylaminopropane, also known as 'NAP' & 'PAL-287'
Substituted phenylisobutylamines (alpha-ethyl-phenethylamines)
- 4-chlorophenylisobutylamine, also known as '4-chloro-α-ethylphenethylamine', '4-CAB', & 'AEPCA'
- 4-Methylphenylisobutylamine, also known as '4-MAB'
- Ariadne, also known as 'α-Et-DOM', '4C-D', & 'Dimoxamine'
Alpha-substituted (-alkylated) tryptamines
- α-methyltryptamine, also known as 'αMT' & 'AMT'
- 5-MeO-αMT
- α-ethyltryptamine, also known as 'αET' & 'AET'
- 4-Me-αET
- 7-Me-αET
- 5-MeO-αET
- 5-MeO-MiPT

Dissociatives (NMDA receptor antagonists)

Arylcyclohexylamines
- Phencyclidine, also known as 'PCP'
- 3-Methoxyphencyclidine, also known as '3-MeO-PCP'
- 4-Methoxyphencyclidine, also known as '4-MeO-PCP'
- Phencyclamine, also known as 'PCPr'
- Rolicyclidine, also known as 'PCPy'
- Eticyclidine, also known as 'PCE'
- Dieticyclidine, also known as 'PCDE'
- Tenocyclidine, also known as 'TCP'
- Gacyclidine, also known as 'GK-11'
- Ketamine, also known as 'Special K'
- Esketamine, also known as '(S)-ketamine'
- Methoxyketamine, also known as '2-MeO-ketamine'
- Methoxetamine, also known as 'MXE'
- Methoxmetamine, also known as 'MXM'
- Deschloroketamine, also known as 'DCK', 'O-PCM', '2'-Oxo-PCM
- Tiletamine
- 3-MeO-PCE
- O-PCE, also known as '2'-Oxo-PCE'
- 2-TFMDCK, also known as '2-Trifluoromethyldeschloroketamine'
- 3-HO-PCE
- 3-HO-PCP
- 3-MeO-PCMo
- 2-Fluorodeschloroketamine, also known as '2-FDCK', 'Fluoroketamine', '2-Fluoroketamine'
- N-Ethylnorketamine, also known as 'NENK', 'N-Ethylketamine'
- Metaphit
- Fourphit
Adamantanes
- Amantadine
- Memantine
- Rimantadine
Diarylethylamines
- Diphenidine, also known as '1,2-DEP', 'DPD', & 'DND'
- Methoxphenidine, also known as 'MXP'
- Ephenidine
- Fluorolintane
- Remacemide
Morphinans
- Dextrallorphan, also known as 'DXA'
- Dextromethorphan, also known as 'DXM'; pro-drug to DXO, yields delirious cognitive effects inofitself (i.e. pre-conversion)
- Dextrorphan, also known as 'DXO'; a natural metabolite of DXM (via liver enzyme P450 2D6), and responsible for the primary 'dissociative' effects of robo-tripping
- Oxilorphan
Nitrous oxide
Neramexane
Xenon
2-MDP
8A-PDHQ
Aptiganel
Chloroform
Dexoxadrol
Diethyl ether
Dizocilpine
Etoxadrol
Midafotel
NEFA
Rhynchophylline
Noribogaine
Perzinfotel
Selfotel

Cannabinoids (CB-1 cannabinoid receptor ligands)

Phytocannabinoids
- Δ⁹-THC #, Agonist[1]; the primary active constituent of cannabis[2] (formerly known as marijuana)
  - 11-hydroxy-Δ⁹-THC, Agonist; An active metabolite of orally administered Δ⁹-THC;[3] Note: Technically not a phytocannabinoid
- CBD #, Negative allosteric modulator[4], another major active constituent of cannabis;
- CBN #, A minor active constituent of cannabis, also a metabolite THC and a product of its degradation
- THCV #, A minor active constituent of cannabis
Synthetic cannabinoids
- (C6)-CP 47,497
- (C9)-CP 47,497
- 1-Butyl-3-(2-methoxybenzoyl)indole
- 1-Butyl-3-(4-methoxybenzoyl)indole
- 1-Pentyl-3-(2-methoxybenzoyl)indole
- 2-Isopropyl-5-methyl-1-
  (2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
- 4-HTMPIPO
- 4-Nonylphenylboronic acid
- 5Br-UR-144
- 5Cl-APINACA
- 5Cl-UR-144
- 5F-3-pyridinoylindole
- 5F-AB-FUPPYCA
- 5F-ADB-PINACA
- 5F-ADBICA
- 5F-ADB
- 5F-AMB
- 5F-APINACA
- 5F-CUMYL-PINACA
- 5F-EMB-PINACA
- 5F-NNE1
- 5F-PB-22
- 5F-PCN
- 5F-PY-PICA
- 5F-PY-PINACA
- 5F-SDB-006
- HHC
- A-796,260
- A-834,735
- A-836,339
- A-955,840
- A-40174
- A-41988
- A-42574
- AB-001
- AB-CHFUPYCA
- AB-CHMFUPPYCA
- AB-CHMINACA
- AB-FUBICA
- AB-FUBINACA 2-fluorobenzyl isomer
- AB-FUBINACA
- AB-PICA
- AB-PINACA
- Abnormal cannabidiol
- ADAMANTYL-THPINACA
- ADB-CHMINACA
- ADB-FUBICA
- ADB-FUBINACA
- ADB-PINACA
- ADBICA
- ADSB-FUB-187
- Ajulemic acid
- AM-087
- AM-411
- AM-630
- AM-630
- AM-679
- AM-694
- AM-855
- AM-883
- AM-905
- AM-906
- AM-919
- AM-926
- AM-938
- AM-1220
- AM-1221
- AM-1235
- AM-1241
- AM-1248
- AM-1346
- AM-1387
- AM-1714
- AM-2201
- AM-2232
- AM-2233
- AM-2389
- AM-4030
- AM-4113
- AM-6527
- AM-6545
- AM-251
- AM-281
- AM-404
- AMB-CHMINACA
- AMB-FUBINACA
- AMG-1
- AMG-3
- AMG-36
- AMG-41
- APICA
- APINACA, also known as 'AKB48'
- APP-FUBINACA
- Arachidonoyl serotonin
- ACEA
- ACPA
- Arvanil
- AZ-11713908
- BAY 38-7271
- BAY 59-3074
- BIM-018
- Biochanin A
- BML-190
- Nabidrox (Canbisol)
- Cannabicyclohexanol
- Cannabipiperidiethanone
- CAY-10401
- CAY-10429
- CAY-10508
- CB-13
- CB-25
- CB-52
- CB-86
- CB-86
- CBS-0550
- CP 47,497
- CP 55,244
- CP 55,940
- CUMYL-5F-PICA
- CUMYL-BICA
- CUMYL-PICA
- CUMYL-PINACA
- CUMYL-THPINACA
- Dexanabinol, also known as 'HU-211'
- Dimethylheptylpyran, also known as 'DMHP'
- Drinabant, also known as 'AVE1625'
- Dronabinol
- EAM-2201
- EMB-FUBINACA
- FAB-144
- FDU-NNE1
- FDU-PB-22
- FUB-144
- FUB-APINACA
- FUB-JWH-018
- FUB-PB-22
- FUBIMINA
- Genistein
- GW-405,833, also known as 'L-768,242'
- GW-842,166X
- Hemopressin
- HU-210
- HU-243
- HU-308
- HU-320
- HU-331
- HU-336
- HU-345
- HU-910
- Ibipinabant, also known as 'SLV319'
- IDFP
- JNJ 1661010
- JTE-907
- JTE 7-31
- JWH-007
- JWH-015
- JWH-018
- JWH-019
- JWH-030
- JWH-051
- JWH-073
- JWH-081
- JWH-098
- JWH-116
- JWH-122
- JWH-133
- JWH-139
- JWH-147
- JWH-149
- JWH-161
- JWH-164
- JWH-167
- JWH-175
- JWH-176
- JWH-182
- JWH-184
- JWH-185
- JWH-192
- JWH-193
- JWH-194
- JWH-195
- JWH-196
- JWH-197
- JWH-198
- JWH-199
- JWH-200
- JWH-203
- JWH-210
- JWH-229
- JWH-249
- JWH-250
- JWH-251
- JWH-302
- JWH-307
- JWH-359
- JWH-369
- JWH-370
- JWH-398
- JWH-424
- JZL184
- JZL195
- Kaempferol
- KM-233
- L-759,633
- L-759,656
- LASSBio-881
- LBP-1
- Leelamine
- Levonantradol, also known as 'CP 50,5561'
- LH-21
- LY-320,135
- LY-2183240
- MAM-2201
- MDA-7
- MDA-19
- MDA-77
- MDMB-CHMICA
- MDMB-CHMINACA
- MDMB-FUBINACA
- Menabitan
- MEPIRAPIM
- Methanandamide, also known as 'AM-356'
- MJ-15
- MK-9470
- MMB-2201
- MN-18
- MN-25, also known as 'UR-12'
- Nabazenil
- Nabilone
- Nabitan
- Naboctate
- NESS-0327
- NESS-040C5
- NIDA-41020
- NM-2201
- NMP-7
- NNE1
- Nonabine
- O-224
- O-581
- O-585
- O-606
- O-689
- O-774
- O-806
- O-823
- O-889
- O-1057
- O-1125
- O-1184
- O-1191
- O-1238
- O-1248
- O-1269
- O-1270
- O-1376
- O-1399
- O-1422
- O-1601
- O-1602
- O-1624
- O-1656
- O-1657
- O-1660
- O-1812
- O-1860
- O-1861
- O-1871
- O-1918
- O-2048
- O-2050
- O-2093
- O-2113
- O-2220
- O-2365
- O-2372
- O-2373
- O-2383
- O-2426
- O-2484
- O-2545
- O-2654
- O-2694
- O-2715
- O-2716
- O-3223
- O-3226
- Oleoylethanolamide, also known as 'OEA'
- Olvanil
- Org 27569
- Org 27759
- Org 28312
- Org 28611
- Org 29647
- Otenabant, also known as 'CP-945,598'
- Palmitoylethanolamide, also known as 'PEA'
- Parahexyl
- PF-03550096
- PF-04457845
- PF-622
- PF-750
- PF-3845
- PF-514273
- PHOP
- PipISB
- Pirnabine
- Pravadoline
- Pregnenolone
- PSB-SB-487
- PSB-SB-1202
- PTI-1
- PTI-2
- PX-1
- PX-2
- PX-3
- QUCHIC, also known as 'BB-22'
- QUPIC, also known as 'PB-22'
- RCS-4
- RCS-8
- Rimonabant, also known as 'SR141716'
- Rosonabant, also known as 'E-6776'
- RTI-371
- S-444,823
- SDB-006
- SER-601
- SPA-229
- SR-144,528
- STS-135
- Surinabant, also known as 'SR147778'
- Taranabant, also known as 'MK-0364'
- Tedalinab
- THC-O-acetate
- THC-O-phosphate
- THJ-018
- THJ-2201
- Tinabinol
- TM-38837
- UR-144
- URB-447
- URB-447
- URB-597
- URB-602
- URB-754
- VCHSR
- VDM-11
- VSN-16
- WIN 54,461
- WIN 55,212-2
- WIN 56,098
- XLR-11
- Yangonin

Other

Harmaline #, harmala alkaloids #, and other beta-carbolines, active constituents of Ayahuasca; powerful MAOIs (can be classified as indoles)
Salvinorin A #, an opioid (κ-opioid receptor agonist), the active constituent of Salvia divinorum sage
Salvinorin B methoxymethyl ether #, a semi-synthetic analogue of the natural product salvinorin A with longer duration and increased affinity and potency at the κ-opioid receptor.
Salvinorin B ethoxymethyl ether #, a semi-synthetic analogue of the natural product salvinorin A with longer duration and increased affinity and potency at the κ-opioid receptor.
Piperazines, such as pFPP and TFMPP, usually classified as stimulants
Myristicin # and Elemicin #, the active constituents of nutmeg
Cryogenine (Vertine) #, the active constituent of certain heimia species
Atropine #, Scopolamine #, and Hyoscyamine #, the active constituents of certain Solanaceae species
Ibotenic acid # and Muscimol #, the active constituents of Amanita muscaria mushrooms

References

Pertwee, R G (April 2006). "The pharmacology of cannabinoid receptors and their ligands: an overview". International Journal of Obesity. 30 (S1): S13–S18. doi:10.1038/sj.ijo.0803272. ISSN 0307-0565. PMID 16570099.
Cannabis and cannabinoids : pharmacology, toxicology, and therapeutic potential. Grotenhermen, Franjo., Russo, Ethan. New York: Haworth Integrative Healing Press. 2002. ISBN 9781136614941. OCLC 606854125.CS1 maint: others (link)
Huestis, M. A. (2005), "Pharmacokinetics and Metabolism of the Plant Cannabinoids, Δ9-Tetrahydrocannibinol, Cannabidiol and Cannabinol", in Pertwee, Roger G. (ed.), Cannabinoids, Handbook of Experimental Pharmacology, 168, Springer-Verlag, pp. 657–690, doi:10.1007/3-540-26573-2_23, ISBN 9783540225652
Laprairie, R B; Bagher, A M; Kelly, M E M; Denovan‐Wright, E M (October 2015). "Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor". British Journal of Pharmacology. 172 (20): 4790–4805. doi:10.1111/bph.13250. ISSN 0007-1188. PMC 4621983. PMID 26218440.

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[1] Pertwee, R G (April 2006). "The pharmacology of cannabinoid receptors and their ligands: an overview". International Journal of Obesity. 30 (S1): S13–S18. doi:10.1038/sj.ijo.0803272. ISSN 0307-0565. PMID 16570099.

[2] Cannabis and cannabinoids : pharmacology, toxicology, and therapeutic potential. Grotenhermen, Franjo., Russo, Ethan. New York: Haworth Integrative Healing Press. 2002. ISBN 9781136614941. OCLC 606854125.CS1 maint: others (link)

[3] Huestis, M. A. (2005), "Pharmacokinetics and Metabolism of the Plant Cannabinoids, Δ9-Tetrahydrocannibinol, Cannabidiol and Cannabinol", in Pertwee, Roger G. (ed.), Cannabinoids, Handbook of Experimental Pharmacology, 168, Springer-Verlag, pp. 657–690, doi:10.1007/3-540-26573-2_23, ISBN 9783540225652

[4] Laprairie, R B; Bagher, A M; Kelly, M E M; Denovan‐Wright, E M (October 2015). "Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor". British Journal of Pharmacology. 172 (20): 4790–4805. doi:10.1111/bph.13250. ISSN 0007-1188. PMC 4621983. PMID 26218440.

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