Testosterone benzoate

Testosterone benzoate, or testosterone 17β-benzoate, also known as androst-4-en-17β-ol-3-one 17β-benzoate, is a synthetic, injected anabolic–androgenic steroid (AAS) and an androgen ester – specifically, the benzoate C17β ester of testosterone – which was never marketed.[1][2] It is a prodrug of testosterone and, when administered via intramuscular injection, is associated with a long-lasting depot effect and extended duration of action.[3][4][5] The drug was first described in 1936 and was the first androgen ester and ester of testosterone to be synthesized.[6]

Testosterone benzoate
Clinical data
Other namesTestosterone 17β-benzoate; Androst-4-en-17β-ol-3-one 17β-benzoate
Routes of
administration		Intramuscular injection
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ECHA InfoCard100.016.575
Chemical and physical data
FormulaC26H32O3
Molar mass392.539 g/mol g·mol−1
3D model (JSmol)

See also

References
  1. Samuel H. Yalkowsky; Yan He; Parijat Jain (19 April 2016). Handbook of Aqueous Solubility Data, Second Edition. CRC Press. pp. 1313–. ISBN 978-1-4398-0246-5.
  2. Trevor Archer; Stefan Hansen (5 September 2013). Behavioral Biology: Neuroendocrine Axis. Psychology Press. pp. 76–. ISBN 978-1-134-76125-8.
  3. CIBA Foundation Symposium (17 September 2009). Hormones, Psychology and Behaviour, Volume 3: Book I of Colloquia on Endocrinology. John Wiley & Sons. pp. 260–. ISBN 978-0-470-71486-7.
  4. Bernd Schaefer (26 May 2015). Natural Products in the Chemical Industry. Springer. pp. 540–. ISBN 978-3-642-54461-3.
  5. Henryk Lamparczyk (21 August 1992). CRC Handbook of Chromatography: Analysis and Characterization of Steroids. CRC Press. pp. 34–. ISBN 978-0-8493-3008-7.
  6. Parkes, A.S. (1936). "Increasing the Effectiveness of Testosterone". The Lancet. 228 (5899): 674–676. doi:10.1016/S0140-6736(00)80929-0. ISSN 0140-6736.


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