Psychotridine

Psychotridine is an alkaloid found in some species of the genus Psychotria, namely Psychotria colorata,[1] but also Psychotria forsteriana,[2] Psychotria lyciiflora,[3] Psychotria oleoides,[3] and Psychotria beccarioides.[4] Psychotridine has analgesic effects and dose-dependently inhibits dizocilpine binding to cortical membranes in vitro, suggesting that it acts as a non-competitive NMDA receptor antagonist.[1]

Psychotridine
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC55H62N10
Molar mass863.15 g/mol g·mol−1
3D model (JSmol)

See also

References
  1. Amador TA, Verotta L, Nunes DS, Elisabetsky E (May 2001). "Involvement of NMDA receptors in the analgesic properties of psychotridine". Phytomedicine. 8 (3): 202–6. doi:10.1078/0944-7113-00025. PMID 11417913.
  2. Beretz A, Roth-Georger A, Corre G, Kuballa B, Anton R, Cazenave JP (August 1985). "Polyindolinic Alkaloids from Psychotria forsteriana. Potent Inhibitors of the Aggregation of Human Platelets". Planta Medica. 51 (4): 300–3. doi:10.1055/s-2007-969496. PMID 17340518.
  3. Jannic V, Guéritte F, Laprévote O, et al. (June 1999). "Pyrrolidinoindoline alkaloids from Psychotria oleoides and Psychotria lyciiflora". Journal of Natural Products. 62 (6): 838–43. doi:10.1021/np9805387. PMID 10395499.
  4. "Psychotridine, a C55H62N10 alkaloid from Psychotria beccarioides (Rubiaceae)". Australian Journal of Chemistry. 27 (3): 639–646. 1974. doi:10.1071/ch9740639.


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