5,7-Dichlorokynurenic acid
5,7-Dichlorokynurenic acid (DCKA) is a selective NMDA receptor antagonist acting at the glycine site of the NMDA receptor complex.[1]
![]() | |
Names | |
---|---|
IUPAC name
5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
ChemSpider | |
PubChem CID |
|
InChI
| |
SMILES
| |
Properties | |
Chemical formula |
C10H5Cl2NO3 |
Molar mass | 258.05 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
![]() ![]() ![]() | |
Infobox references | |
See also
- 7-Chlorokynurenic acid
- Kynurenic acid
References
- McNamara D, Smith EC, Calligaro DO, O'Malley PJ, McQuaid LA, Dingledine R. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neuroscience Letters. 1990 Nov 27;120(1):17-20. PMID 2149877
This article is issued from
Wikipedia.
The text is licensed under Creative
Commons - Attribution - Sharealike.
Additional terms may apply for the media files.