Estradiol dienantate

Estradiol dienantate
Clinical data
Other names	Estradiol dienanthate; Estradiol diheptanoate; Estra-1,3,5(10)-triene-3,17β-diol diheptanoate
Routes of; administration	Intramuscular injection
Drug class	Estrogen; Estrogen ester
Identifiers
	IUPAC name [(8R,9S,13S,14S,17S)-3-heptanoyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] heptanoate;
CAS Number	7732-97-0;
PubChem CID	165688;
DrugBank	DB13955;
ChemSpider	145199;
UNII	65C72P1860;
ECHA InfoCard	100.028.903
Chemical and physical data
Formula	C32H48O4
Molar mass	496.721 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C3C=CC(=C4)OC(=O)CCCCCC)C;
	InChI InChI=1S/C32H48O4/c1-4-6-8-10-12-30(33)35-24-15-17-25-23(22-24)14-16-27-26(25)20-21-32(3)28(27)18-19-29(32)36-31(34)13-11-9-7-5-2/h15,17,22,26-29H,4-14,16,18-21H2,1-3H3/t26-,27-,28+,29+,32+/m1/s1; Key:OVAHZPTYWMWNKO-CAHAWPIUSA-N;

Estradiol dienantate, or estradiol 3,17-dihepanoate, is an estrogen and an estrogen ester.[1] It is the C3 and C17β dienanthate (diheptanoate) ester of estradiol.[1] The medication is a component of Climacteron, an injectable combination formulation of testosterone enantate benzilic acid hydrazone, estradiol dienantate, and estradiol benzoate which was previously used in the treatment of menopausal symptoms in women.[2][3][4]

References

J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
Ginsburg, Elizabeth S. (1999). "Androgen Replacement in Postmenopausal Women". In Seifer, David B.; Kennard, Elizabeth A. (eds.). Menopause. 18. pp. 209–219. doi:10.1007/978-1-59259-246-3_13. ISBN 978-1-61737-129-5.
Robert B. Greenblatt; William E. Barfield; Edwin C. Jungck (January 1962). "The treatment of the menopause". Can Med Assoc J. 86 (3): 113–4. PMC 1848811. PMID 13901504.
David B. Seifer (27 July 1999). Menopause: Endocrinology and Management. Springer Science & Business Media. pp. 183–. doi:10.1007/978-1-59259-246-3. ISBN 978-1-59259-246-3.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.