Diethylstilbestrol monobenzyl ether
Diethylstilbestrol monobenzyl ether (brand names Monozol, Hypantin, Pituitrope), also known as benzelstilbestrol, is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ether of diethylstilbestrol (DES) that is described as a pituitary gland inhibitor (antigonadotropin) and was formerly marketed but is now no longer available.[1][2] It was first synthesized by Wallace & Tiernan Company in 1952, and was described by them as having only weak estrogenic activity.[3] The drug was used to treat gynecological conditions and infertility in women.[2]
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| Trade names | Monozol, Hypantin, Pituitrope |
| Other names | Benzelstilbestrol |
| Drug class | Nonsteroidal estrogen; Estrogen ether |
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| Formula | C25H26O2 |
| Molar mass | 358.473 g/mol g·mol−1 |
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References
- J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 397. ISBN 978-1-4757-2085-3.
- Margaret Marsh; Wanda Ronner (29 December 2010). The Fertility Doctor: John Rock and the Reproductive Revolution. JHU Press. pp. 144–. ISBN 978-1-4214-0208-6.
- Ronald George Harrison (1957). Studies on Fertility. Blackwell. pp. 135–136.
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