Dimenoxadol

Dimenoxadol (INN) (brand name Estocin (in Russia)), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

Dimenoxadol
Clinical data
Other namesDimenoxadol, Estocin
ATC code
  • none
Legal status
Legal status
  • AU: S9 (Prohibited)
  • CA: Schedule I
  • DE: Anlage I (Authorized scientific use only)
  • US: Schedule I
  • UN: Psychotropic Schedule I
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H25NO3
Molar mass327.42 g/mol g·mol−1
3D model (JSmol)
  (verify)

It was invented in Germany in the 1950s,[1] and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.[2][3][4]

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9617 and a 2013 annual aggregate manufacturing quota of zero.

References
  1. GB 716700, Boehringer, A et al., "A new and improved analgesic and process for its production", published 10/13/1954
  2. Gorbatova, E. N. (1967). "The pharmacology of estocin, an new analgesic". Stomatologiia. 46 (2): 22–25. PMID 5232927.
  3. Kingisepp, G. A.; Kurvits, K.; Nurmand, L. B. (1969). "Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin". Farmakologiia i toksikologiia. 32 (6): 710–712. PMID 5381602.
  4. Liberman, S. S. (1968). "Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)". Farmakologiia i toksikologiia. 31 (6): 668–671. PMID 5729519.


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