Nope, try again. Forty years after the 1964 Surgeon General’s Report, the 2004 Surgeon General’s Report found that smoking is even more destructive to the human body than originally thought. Nearly every organ in the body is damaged by smoke, from the kidneys to the brain. Smoking can lead to cancer of the mouth, lung, throat, stomach, kidneys, bladder and pancreas, asthma and ulcers.