MR-2096
MR-2096 is an opioid analgesic drug related to oxymorphone. It has an unusual chiral tetrahydrofuran-2-ylmethyl substitution on the nitrogen which determines the character of effects, with the (R) enantiomer MR-2096 being an opioid agonist, while the (S) enantiomer MR-2097 has similarly potent opioid antagonist effects. This mix of activities has made these two enantiomers useful for characterising the binding site of the mu opioid receptor.[1]
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Formula | C21H25NO5 |
Molar mass | 371.43 g/mol g·mol−1 |
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References
- Ramabadran, K.; Jen, M. F. (1985). "Opioid agonist and antagonist properties of diastereoisomeric N-tetrahydronoroxymorphones in mice". Archives Internationales de Pharmacodynamie et de Thérapie. 274 (2): 180–188. PMID 4040738.
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