Furethidine

Furethidine[1] is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).[2]

Furethidine
Clinical data
Other namesethyl 4-phenyl-1-(2-tetrahydrofurfuryloxyethyl)piperidine-4-carboxylate
ATC code
  • none
Legal status
Legal status
  • AU: S9 (Prohibited)
  • CA: Schedule I
  • DE: Anlage I (Authorized scientific use only)
  • UK: Class A
  • US: Schedule I
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.017.451
Chemical and physical data
FormulaC21H31NO4
Molar mass361.48 g/mol g·mol−1
3D model (JSmol)
  (verify)

Furethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.[3] In the United States it is a Schedule I Narcotic controlled substance with the ACSCN of 9626.[4]

References
  1. GB Patent 797448
  2. Maul C, Buschmann H, Sundermann B. Opioids: 3.3 Synthetic Opioids. Analgesics 2005; 159-169. ISBN 978-3-527-30403-5
  3. Cahal DA, Dare JG, Keith D. A Sequential Trial of Analgesics in Labour. International Journal of Obstetrics and Gynaecology 1961; 68(1): 88–93.
  4. http://www.deadiversion.usdoj.gov/schedules/orangebook/d_cs_drugcode.pdf, pp. 13, accessed 23. January 2016



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