Adiponectin receptor

The adiponectin receptors (AdipoRs) include the following two receptors, which are bound and activated by adiponectin:

  • Adiponectin receptor 1 (AdipoR1, PAQR1)
  • Adiponectin receptor 2 (AdipoR2, PAQR2)

They are members of the progestin and adipoQ receptor (PAQR) family.[1]

In 2016, the University of Tokyo announced it was launching an investigation into anonymously made claims of fabricated and falsified data on the identification of AdipoR1 and AdipoR2.[2]

References

  1. Tang, Y. Tom; Hu, Tianhua; Arterburn, Matthew; Boyle, Bryan; Bright, Jessica M.; Emtage, Peter C.; Funk, Walter D. (2005). "PAQR Proteins: A Novel Membrane Receptor Family Defined by an Ancient7-Transmembrane Pass Motif". Journal of Molecular Evolution. 61 (3): 372–380. doi:10.1007/s00239-004-0375-2. ISSN 0022-2844. PMID 16044242.
  2. University of Tokyo to investigate data manipulation charges against six prominent research groups ScienceInsider, Dennis Normile, Sep 20, 2016



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