Nocardicin A

Nocardicin A is a monocyclic β-lactam antibiotic included in the monobactam subclass. It is obtained from the fermentation broth of a strain of actinomycetes Nocardia uniformis subsp. tsuyamenensis as a metabolic product catalyzed by the enzyme nocardicin-A epimerase. It is stereochemically and biologically related to penicillin and cephalosporins.

Biosynthesis of Nocardicin A
Nocardicin A
Names
IUPAC name
(2R)-2-Amino-4-[4-[N-hydroxy-C-[[(3S)-1- [(1R)-2-hydroxy-1-(4-hydroxyphenyl)-2- oxoethyl]-2-oxoazetidin-3- yl]carbamoyl]carbonimidoyl]phenoxy]butanoic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
Properties
Chemical formula
C23H24N4O9
Molar mass 500.46 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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