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Slide 23. Primary Isoniazid Resistance in U.S.-born vs. Foreign-born Persons, United States, 1993–2012. This graph shows primary isoniazid resistance in U.S.-born vs. foreign-born persons. Based on initial isolates from persons with no prior history of TB, the percentage of isoniazid resistance is more than twice as high among foreign-born persons than among U.S.-born persons. In foreign-born persons, the percentage declined from 12.1% in 1993 to 10.7% in 2012. In U.S.-born persons, the percentage decreased from 6.7% in 1993 to 4.2% in 2007, but has increased since then to 5.7% in 2012.
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