Invasive Candidiasis Risk & Prevention

Most cases of invasive candidiasis occur in people who have recently been admitted to a hospital or been in contact with other healthcare settings such as nursing homes. People who are at high risk for developing invasive candidiasis include:1

  • Patients who have a central venous catheter
  • Patients in the intensive care unit (ICU)
  • People who have weakened immune systems (for example, people who have had an organ transplant,  have HIV/AIDS, or are on cancer chemotherapy)
  • People who have taken broad-spectrum antibiotics
  • People who have a very low neutrophil (a type of white blood cell) count (neutropenia)
  • People who have kidney failure or are on hemodialysis
  • Patients who have had surgery, especially gastrointestinal surgery
  • Patients who have diabetes

References

  1. Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev. 2007 Jan;20(1):133-63.
  2. Strausbaugh LJ, Sewell DL, Ward TT, Pfaller MA, Heitzman T, Tjoelker R. High frequency of yeast carriage on hands of hospital personnel. J Clin Microbiol. 1994 Sep;32(9):2299-300.
  3. Yildirim M, Sahin I, Kucukbayrak A, Ozdemir D, Tevfik Yavuz M, Oksuz S, et al. Hand carriage of Candida species and risk factors in hospital personnel. Mycoses. 2007 May;50(3):189-92.
  4. Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016 Feb 15;62(4):e1-e50.
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