Nacolomab tafenatox
Nacolomab tafenatox is a mouse monoclonal antibody[1] designed for the treatment of colorectal cancer. The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]

Schematic image of nacolomab tafenatox.
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)
Monoclonal antibody | |
---|---|
Type | Fab fragment |
Source | Mouse |
Target | colorectal tumor antigen C242 |
Clinical data | |
ATC code |
|
Identifiers | |
CAS Number | |
ChemSpider |
|
![]() ![]() |
See also
- Naptumomab estafenatox, a drug with a similar chemical structure and mechanism
This article is issued from
Wikipedia.
The text is licensed under Creative
Commons - Attribution - Sharealike.
Additional terms may apply for the media files.