ID Week Presentations

• A Prospective Study of Transmission of Multi-drug Resistant Organisms (MDRO) between Environmental Sites and Hospitalized Patients – the TransFER study
  Luke F. Chen, MBBS, MPH, CIC, FRACP1,2,3, Lauren Knelson, MSPH3, Maria Gergen, MT, ASCP4, Olga Better, RA5, Bradley Nicholson, PhD6, Sarah S. Lewis, MD MPH1, Christopher W Woods, MD, MPH, FIDSA7, William Rutala, PhD, MPH, FSHEA3, David J. Weber, MD, MPH, FIDSA, FSHEA8, Rebekah W. Moehring, MD, MPH1, Daniel J. Sexton, MD, FIDSA, FSHEA1 and Deverick Anderson, MD, MPH, FIDSA, FSHEA1
  • Session: 126. Preventing Hospital Transmission: Environment and Hands
  • Location: Room: 7–AB
  • Date: Friday, October 9, 2015 @ 10:30 am
• Self-monitoring of hospital room cleaning by Environmental Services (EVS) may not accurately measure cleanliness
  Lauren P. Knelson, MSPH1,2,3, Gemila Ramadanovic, LPN4, Luke F. Chen, MBBS, MPH, CIC, FRACP1,2,3, Rebekah W. Moehring, MD, MPH1,2,3,5, Sarah S. Lewis, MD MPH1,2,3, William Rutala, PhD, MPH, FSHEA6,7, David J. Weber, MD, MPH, FIDSA, FSHEA8,9,10, Daniel J. Sexton, MD, FIDSA, FSHEA2,3, Deverick Anderson, MD, MPH, FIDSA, FSHEA1,2,3,5 and CDC Prevention EpiCenter Program  
  • Session: 126. Preventing Hospital Transmission: Environment and Hands
  • Location: Room: 7–AB
  • Date: Friday, October 9, 2015 @ 10:30 AM-12:00 PM
• The Benefits of Enhanced Terminal Room (BETR) Disinfection Study: A Cluster Randomized, Multicenter Crossover Study with 2×2 Factorial Design to Evaluate the Impact of Enhanced Terminal Room Disinfection on Acquisition and Infection Caused by Multidrug-Resistant Organisms (MDRO)
  Luke F. Chen, MBBS, MPH, CIC, FRACP1, David J. Weber, MD, MPH, FIDSA, FSHEA2, Rebekah W. Moehring, MD, MPH1, Sarah S. Lewis, MD MPH1, Patricia Triplett, MD3, Michael Blocker, MD4, Paul Becherer, MD5, J. Conrad Schwab, MD6, Lauren P. Knelson, MSPH1, Yuliya Lokhnygina, MS, PhD7, William Rutala, PhD, MPH, FSHEA8, Daniel J. Sexton, MD, FIDSA, FSHEA1 and CDC Prevention Epicenters Program  
  • Session: SHEA Featured Abstract
  • Location: Room: 20–ABCD
  • Date: Friday, October 9, 2015 @ 4:15 pm
• Risk factors for acquisition of rectal colonization with KPC-producing Enterobacteriaceae (KPC) among long-term acute care hospital (LTACH) patients.
  Okamoto K, Lin MY, Haverkate M, Lolans K, Moore NM, Weiner S, Lyles RD, Blom D, Rhee Y, Kemble S, Fogg L, Hines DW, Weinstein RA, Hayden MK for the CDC Prevention Epicenters Program.  
  • Session: Oral Abstract Session: Antimicrobial Stewardship in Older Adults
  • Location: Room: 25–ABC
  • Date: Saturday, October 10, 2015: 8:30 AM
• Epidemiology of the beta-lactamase resistome among Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae in the Chicago region.
  Lin MY, Lolans K, Lyles RD, Wagner TK, Walker GT, Weinstein RA, Hayden MK for the CDC Prevention Epicenter Program  
  • Session: Oral Abstract Session: Epidemiology of Resistant Gram Negative Infections
  • Location: Room: 5–AB
  • Date: Saturday, October 10, 2015: 10:30 AM
• Genomic Epidemiology of an Early, Regional Outbreak of blaKPC-encoding Klebsiella pneumoniae (KPC).
  Snitkin ES, Won S, Lolans K, Whitefield S, Weinstein RA, Popovich K, Munoz-Price LS, Lin MY, Hayden MK for the CDC Prevention Epicenters Program.  
  • Session: Oral Abstract Session: Epidemiology of Resistant Gram Negative Infections
  • Location: Room: 5–AB
  • Date: Saturday, October 10, 2015: 10:45 AM
• Clinical and Molecular Characterization of Community-Onset Urinary Tract Infections due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae
  Jennifer Han, MD, MSCE1, Irving Nachamkin, DrPH, MPH, FIDSA2, Charles Garrigan, MB2, Warren Bilker, PhD3, Mary K. Wheeler, MBE3, Pam Tolomeo, MPH3, Ebbing Lautenbach, MD, MPH, MSCE, FIDSA, FSHEA4 and for the CDC Prevention Epicenters Program,  
  • Session: 247. Resistant Gram Negative Infections: Epidemiology, poster abstract
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015 @ 12:30-2:00PM
• The Molecular Epidemiology of Extended-Spectrum Beta-Lactamase (ESBL) and Klebsiella pneumoniae Carbapenemase producing Enterobacteriaceae (CRE) in Chicago Children: A Multi-Center Study.
  Logan LK, Marshall SM, Hujer AM, Hujer AM, Dimitrovic TN, Rudin SD, Scaggs FA, Karadkhele A, Zheng XT, Qureshi N, Hayden MK, Bonomo RA.  
  • Session: Poster Abstract Session: Pediatric Bacterial Infections
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015
• Chlorhexidine Gluconate (CHG) susceptibility of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates from skin cultures of patients in long-term acute care hospitals (LTACHs).
  Moore NM, Lolans K, Fogg L, Weiner S, Blom D, Lyles RD, Lin MY, Hines DW, Weinstein RA, Hayden MK for the CDC Prevention Epicenters Program.  
  • Session: Poster Abstract Session: Resistant Gram Negative Infections: CRE Epidemiology
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015
• Klebsiella pneumoniae carbapenemase (KPC) producing Enterobacteriaceae infections in children: A two-center study.
  Scaggs FA, Charnot-Katsikas A, Bartlett AH, Zheng X, Karadkhele A, Weinstein RA, and Logan LK.  
  • Session: Poster Abstract Session: Outbreaks of Bad Bugs and Prevention in Children
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015

• The Food of Hospitalized Patients as a Risk Factor for Acquisition of Clostridium difficile: A Modeling Study
  Jennie H. Kwon, Cristina Lanzas, Kimberly A. Reske, Tiffany Hink, Sondra Seiler, Carey-Ann D. Burnham, Erik R. Dubberke  
  • Session: Poster Abstract Session: Clostridium difficile Infections: Epidemiology and Diagnostics
  • Location: San Diego Convention Center Poster Hall
  • Date: Friday, October 9, 2015 @ 8:30 am
• Evaluation of Community-Acquired Clostridium difficile infection (CA-CDI) in North Carolina (NC) using Geographic Information Systems (GIS) and spatial statistics
  Leoncio Flavio Rojas, Ph.D.1, Shera Watson, MPH2,3, Lauren P. Knelson, MSPH2,4, Sohayla Pruitt, MA5, Sarah S. Lewis, MD MPH2,4, Rebekah W. Moehring, MD, MPH2,4, Luke F. Chen, MBBS, MPH, CIC, FRACP2,4, Daniel J. Sexton, MD, FIDSA, FSHEA2,4, Deverick Anderson, MD, MPH, FIDSA, FSHEA2,4 and CDC Prevention Epicenters Program,  
  • Session: 26. Clostridium difficile Infections: Prophylaxis and Epidemiology
  • Location: Room: 5–AB
  • Date: Thursday, October 8, 2015: 9:30 AM
• Reducing Clostridium difficile Infection among Hematology-Oncology Patients Using Ultraviolet Germicidal Irradiation for Terminal Room Disinfection
  Pegues D, Gilmar C, Denno M, Gaynes S  
  • Session: 240. Infection Prevention: Cleaning and Disinfection
  • Location: Poster Abstract Session: Infection Prevention: Cleaning and Disinfection
  • Date: Saturday, October 10, 2015 @ 12:30 PM – 2:00 PM
• Hospital-wide Evaluation of Probiotic Administration as Primary Prevention of Clostridium difficile infection (CDI) in a Tertiary Care Hospital.
  Trick WE, Sokalski S, Levato J, Sweis R, Velee S, Johnson S, Weinstein RA for the CDC Prevention Epicenter Program.  
  • Session: Poster Abstract Session: Clostridium difficile Infections: Treatment and Prevention
  • Location: Poster Hall
  • Date: Friday, October 9, 2015
• The Food of Hospitalized Patients as a Risk Factor for Acquisition of Clostridium difficile: A Modeling Study
  Jennie H. Kwon, D.O.1, Cristina Lanzas, DVM, PhD2, Kimberly Reske, MPH1, Tiffany Hink, BS1, Sondra Seiler, BA1, Carey-Ann D. Burnham, PhD3 and Erik R. Dubberke, MD, MSPH1, (1)Infectious Diseases, Washington University School of Medicine, St. Louis, MO, (2)Department of Population Health and Pathobiology, North Carolina State University, Raleigh, NC, (3)Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO  
  • Session: Poster Abstract Session: Clostridium difficile Infections: Epidemiology and Diagnostics
  • Location: Poster Hall
  • Date: Friday, October 9, 2015

• Comparison of Stool versus Rectal Swab Samples from Long-Term Acute Care Hospital (LTACH) Patients for Microbiota Analysis.
  Bassis CM, Seekatz A, Moore NM, Lolans K, Weinstein RA, Young VB, Hayden MK for the CDC Prevention Epicenters Program.  
  • Session: Poster Abstract Session: All Things Microbiome
  • Location: Poster Hall
  • Date: Friday, October 9, 2015
• Alteration of the microbial community of the gut in response to fecal microbiota transplantation in subjects with Clostridium difficile infection
  Amy Langdon, Kim Reske, Sherry Sun, Tiffany Hink, Courtney Jones, Carey-Ann D. Burnham, Erik R. Dubberke, Gautam Dantas  
  • Session: 116. Microbiome
  • Location: Room 25—ABC
  • Date: October 9, 2015 @ 9:00 AM-9:15 AM
• Autologous fecal microbiota transplantation as a strategy to prevent colonization with multi-drug resistant organisms following antimicrobial therapy
  Christopher Bulow, Tiffany Hink, Meghan Wallace, Kim Reske, Sherry Sun, Jennie H. Kwon, Carey-Ann D. Burnham, Gautam Dantas, Erik R. Dubberke  
  • Session: Poster Abstract Session: All things Microbiome (129)
  • Location: Poster Hall
  • Date: October 9, 2015 @ 12-2 pm

Infection-related ventilator-associated complications (iVAC) in neonates and children: Can we identify it? 
Cocoros N, Sandora TJ, Logan LK, Coffin S, Priebe GP, Shaklee Sammons J, Larsen G, Toltzis P, Horan K, Miroshnik I, Burton M, Checchia PA, Klompas M, Lee G.  

• Session: Oral Abstract Session: Device and Procedure Related HAIs
• Location: Room 32—ABC
• Date: Friday, October 9, 2015: 3:00 PM

• What Parents Think About Antibiotics for Their Child’s Acute Respiratory Tract Infection
  E. Szymczak, PhD1, Sarah B. Klieger, MPH2, Neika Vendetti, MPH3, Matthew Miller, B.S.4, Alexander Fiks, MD, MSCE4 and Jeffrey S. Gerber, MD, PhD2  
  • Session: Poster Abstract Session 42. Antimicrobial Stewardship: Current State and Future Opportunities
  • Location: Poster Hall
  • Date: Thursday, October 8, 2015
• Improving Documentation and Coding for Acute Organ Dysfunction Biases Severe Sepsis Surveillance Over Time
  Chanu Rhee, MD, MPH1, Michael V. Murphy, BA1, Lingling Li, ScD1, Richard Platt, MD, MS, FIDSA, FSHEA1, Michael Klompas, MD, MPH, FRCPC, FIDSA1 and CDC Prevention Epicenters  
  • Session: Oral Abstract Session: HAI Reporting: The Devil is in the Details
  • Location: Room 5—AB
  • Date: October 8, 2015: 2:15 pm
• Automated Outbreak Detection of Hospital-Associated Infections
  Meghan Baker, MD, ScD1, Deborah S. Yokoe, MD, MPH, FIDSA, FSHEA2, John Stelling, MD, MPH3, Rebecca E. Kaganov, BA1, Alyssa R. Letourneau, MD, MPH4, Thomas O’brien, MD5, Martin Kulldorff, PhD6, Damilola Babalola, MD, MPH7, Craig Barrett, Pharm.D, BCPS8, Marci Drees, MD, MS9, Richard Platt, MD, MS, FIDSA, FSHEA6, Susan S. Huang, MD, MPH, FIDSA, FSHEA10 and For the CDC Prevention Epicenters Program,  
  • Session: Oral Abstract Session: HAI Reporting: The Devil is in the Details
  • Location: Room 5—AB
  • Date: Thursday, October 8, 2015: 3:15 PM
• Developing a Biomarker-Driven Algorithm to Improve Antibiotic Use in the Pediatric Intensive Care Unit: the Optimizing Antibiotic Strategies in Sepsis (OASIS) Study
  Downes K, Weiss S, Kleiger S, Fitzgerald J, Balamuth F, Kubis S, Tolomeo P, Bilker W, Han X, Nachamkin I, Garrigan C, Han J, Lautenbach E, Gerber J, Coffin S, for the CDC Prevention Epicenters Program.  
  • Session: Oral Abstract Session: Pediatric Antimicrobial Stewardship
  • Location: Room 5—AB
  • Date: Friday, October 9, 2015: 2:15 PM
• Use of a Combination Biomarker Algorithm to Identify Intensive Care Unit Patients with Suspected Sepsis at Very Low Likelihood of Bacterial Infection
  Han JH, Nachamkin I, Coffin SE, Gerber J, Garrigan C, Han X, Bilker WB, Wise J, Tolomeo P, Lautenbach E, for the Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program  
  • Session: 217. Antimicrobial Stewardship: Role of Diagnostics
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015
• Impact of an Infectious Diseases Transitions Service on Outcomes in Patients Discharged on Parenteral Antibiotics Requiring Therapeutic Drug Monitoring.
  Julianne Gardner, PharmD; Jillian Dougherty, PharmD; Daniel Timko, PharmD, BCPS (AQ-ID); Shawn Binkley, PharmD; Steven Morgan, PharmD, BCPS (AQ-ID); Valerie Cluzet, MD; Sara Keller, MD, MPH, MSHP; David Pegues, MD; Keith Hamilton, MD  
  • Session: 215. Poster Abstract Session: Antimicrobial Stewardship: Outpatient Parenteral Antibiotic Therapy
  • Location: Poster Hall
  • Date: Saturday, October 10, 2015