Fluoroethyl-L-tyrosine (¹⁸F)

Fluoroethyl-l-tyrosine (¹⁸F)
Clinical data
Other names	18F-FET; O-(2-(18F)fluoroethyl)-l-tyrosine, O-(2-Fluorethyl)-l-thyrosine, l-(18F)FET[1]
Routes of; administration	Intravenous
ATC code	V09IX10 (WHO) ;
Identifiers
	IUPAC name (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid;
PubChem CID	9834479;
ChemSpider	8010200;
UNII	3Y68K91A3M;
Chemical and physical data
Formula	C11H14FNO3
Molar mass	227.23 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CC(=CC=C1C[C@@H](C(=O)O)N)OCC[18F];
	InChI InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1; Key:QZZYPHBVOQMBAT-LRAGLOQXSA-N;

Fluoroethyl-l-tyrosine (¹⁸F) or ¹⁸F-FET is a neuro-oncologic PET tracer.[2]

References

CID 54255856 from PubChem
Galldiks, N.; Stoffels, G.; Filss, C.; Rapp, M.; Blau, T.; Tscherpel, C.; Ceccon, G.; Dunkl, V.; Weinzierl, M.; Stoffel, M.; Sabel, M.; Fink, G. R.; Shah, N. J.; Langen, K.-J. (2015). "The use of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma". Neuro-Oncology. doi:10.1093/neuonc/nov088. PMC 4588758.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.