Hydroflumethiazide

Hydroflumethiazide
Clinical data
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ATC code
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CAS Number
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ECHA InfoCard100.004.704
Chemical and physical data
FormulaC8H8F3N3O4S2
Molar mass331.29 g/mol g·mol−1
3D model (JSmol)
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Hydroflumethiazide (or Saluron) is a diuretic.

Synthesis

Hydroflumethiazide synthesis:[1][2][3] Numerous patents, e.g., Lund et al., U.S. Patent 3,254,076 (1966 to Lövens Kemiske Fabrik).

See also

References

  1. Holdrege, C. T.; Babel, R. B.; Cheney, L. C. (1959). "Synthesis of Trifluoromethylated Compounds Possessing Diuretic Activity1". Journal of the American Chemical Society. 81 (18): 4807. doi:10.1021/ja01527a015.
  2. Close, W. J.; Swett, L. R.; Brady, L. E.; Short, J. H.; Vernsten, M. (1960). "Synthesis of Potential Diuretic Agents. I. Derivatives of 7-Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-Dioxide". Journal of the American Chemical Society. 82 (5): 1132. doi:10.1021/ja01490a028.
  3. Novello, F. C.; Bell, S. C.; Abrams, E. L. A.; Ziegler, C.; Sprague, J. M. (1960). "Diuretics: 1,2,4-Benzothiadiazine-1,1-dioxides". The Journal of Organic Chemistry. 25 (6): 970. doi:10.1021/jo01076a028.


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