Mersalyl

Mersalyl
Names
	IUPAC name (3-{[2-(Carboxymethoxy)benzoyl]amino}-2-methoxypropyl)(hydroxy)mercury
	Other names Mersalyl acid, salyrganic acid
Identifiers
CAS Number	486-67-9 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1201330 ;
ChemSpider	11337655 ;
ECHA InfoCard	100.006.943
IUPHAR/BPS	5331;
PubChem CID	443130;
UNII	5X1IO031V8;
	InChI InChI=1S/C13H16NO5.Hg.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;1H2/q;+1;/p-1 Key: HQRSUIDICNOLPX-UHFFFAOYSA-M ; InChI=1/C13H16NO5.Hg.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;1H2/q;+1;/p-1/rC13H17HgNO6/c1-20-9(6-14-19)7-15-13(18)10-4-2-3-5-11(10)21-8-12(16)17/h2-5,9,19H,6-8H2,1H3,(H,15,18)(H,16,17) Key: HQRSUIDICNOLPX-SCJHNVIKAK;
	SMILES O[Hg]CC(OC)CNC(=O)c1ccccc1OCC(O)=O;
Properties
Chemical formula	C13H18HgNO6
Molar mass	484.87512 g/mol
Pharmacology
ATC code	C03BC01 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Mersalyl (Mersal) is an organomercury compound[1] (mercurial diuretic). It is only rarely used as a drug, having been superseded by diuretic medications that do not contain mercury and are therefore less toxic. It features a Hg(II) centre. Mersalyl was originally adapted from calomel (HgCl), a diuretic discovered by Paracelsus.

References

Stewart, J. H.; Edwards, K. D. (1965). "Clinical comparison of frusemide with bendrofluazide, mersalyl, and ethacrynic acid". British Medical Journal. 2 (5473): 1277–1281. doi:10.1136/bmj.2.5473.1277. PMC 1846704. PMID 5849145.

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[1] Stewart, J. H.; Edwards, K. D. (1965). "Clinical comparison of frusemide with bendrofluazide, mersalyl, and ethacrynic acid". British Medical Journal. 2 (5473): 1277–1281. doi:10.1136/bmj.2.5473.1277. PMC 1846704. PMID 5849145.