Deltapapillomavirus

Deltapapillomavirus is a genus of viruses, in the family Papillomaviridae[1]. Ruminants serve as natural hosts. There are currently seven species in this genus including the type species Deltapapillomavirus 1. Diseases associated with this genus include: warts (papillomas and fibropapillomas) of the skin and alimentary tract (rarely cancers of the alimentary tract and urinary bladder); possibly responsible for the skin tumour equine sarcoid in horses and donkeys.[2][3]

Deltapapillomavirus
Virus classification
Group:
Group I (dsDNA)
Family:
Papillomaviridae
Genus:
Deltapapillomavirus
Type Species
  • Deltapapillomavirus 1

Taxonomy

Group: dsDNA

[3]

Structure

Viruses in Deltapapillomavirus are non-enveloped, with icosahedral geometries. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
DeltapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Ruminants serve as the natural host. Transmission routes are contact.[2]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
DeltapapillomavirusRuminantsEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact

References
  1. Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
  2. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  3. "ICTV Report Papillomaviridae".
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