Inoviridae

Inoviridae is a family of bacteriophage viruses. The genomes are composed of circular single-stranded DNA. Bacteria serve as natural hosts. There are, as of 2014, 43 defined species in this family, divided between two genera.[1][2] However, mining of genomic and metagenomic datasets using machine learning approach led to the discovery of 10,295 inovirus-like sequences in nearly all bacterial phyla across virtually every ecosystem, indicating that this group of viruses is much more diverse and widespread than originally appreciated.[3]

Inoviridae
Virus classification
(unranked): Virus
Phylum: incertae sedis
Class: incertae sedis
Order: incertae sedis
Family: Inoviridae
Genera

Taxonomy

Group: ssDNA

Order: Unassigned
  • Family: Inoviridae
    • Genus: Inovirus
      • Enterobacteria phage AE2
      • Enterobacteria phage C-2
      • Enterobacteria phage dA
      • Enterobacteria phage Ec9
      • Enterobacteria phage f1
      • Enterobacteria phage fd
      • Enterobacteria phage HR
      • Enterobacteria phage I2-2
      • Enterobacteria phage If1
      • Enterobacteria phage IKe
      • Enterobacteria phage M13
      • Enterobacteria phage PR64FS
      • Enterobacteria phage SF
      • Enterobacteria phage tf-1
      • Enterobacteria phage X
      • Enterobacteria phage X-2
      • Enterobacteria phage ZJ/2
      • Pseudomonas phage Pf1
      • Pseudomonas phage Pf2
      • Pseudomonas phage Pf3
      • Vibrio phage 493
      • Vibrio phage CTX
      • Vibrio phage fs1
      • Vibrio phage fs2
      • Vibrio phage v6
      • Vibrio phage Vf12
      • Vibrio phage Vf33
      • Vibrio phage VSK
      • Xanthomonas phage Cf16
      • Xanthomonas phage Cf1c
      • Xanthomonas phage Cf1t
      • Xanthomonas phage Cf1tv
      • Xanthomonas phage Lf
      • Xanthomonas phage Xf
      • Xanthomonas phage Xfo
      • Xanthomonas phage Xfv
    • Genus: Plectrovirus
      • Acholeplasma phage MV-L51
      • Spiroplasma phage 1-aa
      • Spiroplasma phage 1-C74
      • Spiroplasma phage 1-KC3
      • Spiroplasma phage 1-R8A2B
      • Spiroplasma phage 1-S102
      • Spiroplasma phage 1-T78

[2]

Structure

Viruses in Inoviridae are non-enveloped, with rod or filament geometries. The diameter is around 7 nm, with a length of 2000 nm. Genomes are circular, around 8 kb in length. The genome codes for 4 to 10 proteins.[1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
PlectrovirusRod-shapedNon-envelopedCircularMonopartite
InovirusRod-shapedNon-envelopedCircularMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by pilus-mediated adsorption into the host cell. Replication follows the ssDNA rolling circle model. DNA-templated transcription is the method of transcription. The virus exits the host cell by viral extrusion. Bacteria serve as the natural host.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
PlectrovirusBacteriaNonePilus adsorptionSecretionCytoplasmCytoplasmPilus
InovirusGram-negative bacteriaNonePilus adsorptionSecretionCytoplasmCytoplasmPilus

References
  1. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 June 2015.
  3. Roux, S; Krupovic, M; Daly, RA; Borges, AL; Nayfach, S; Schulz, F; Sharrar, A; Matheus Carnevali, PB; Cheng, JF; Ivanova, NN; Bondy-Denomy, J; Wrighton, KC; Woyke, T; Visel, A; Kyrpides, NC; Eloe-Fadrosh, EA (2019). "Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth's biomes". Nature Microbiology. doi:10.1038/s41564-019-0510-x. PMID 31332386.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.