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Malaria Information and Prophylaxis, by Country [C]

The information presented in this table is consistent 1 with the information in the CDC Health Information for International Travel (the “Yellow Book,” New for 2018).
Click on the linked country name for a malaria map of that country.

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Country Areas with Malaria Estimated relative risk of Malaria for US Travelers 2 Drug Resistance3 Malaria Species4 Recommended Chemoprophylaxis5 Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries
Cambodia Present throughout the country including Siem Reap city. None in the city of Phnom Penh and the temple complex at Angkor Wat. Low Chloroquine

Mefloquine

P. falciparum 86%

P. vivax 12%

P. malariae 2%,

P. knowlesi rare

In the provinces of Banteay Meanchey, Battambang, Kampot, Koh Kong, Odder Meanchey, Pailin, Preah Vihear, Pursat, and Siem Reap bordering Thailand: Atovaquone-proguanil or doxycycline

All other areas with malaria: Atovaquone-proguanil, doxycycline, or mefloquine

Cameroon All High Chloroquine P. falciparum >85%

P. ovale 5-10%

P. vivax rare

Atovaquone-proguanil, doxycycline, or mefloquine
Canada None None Not Applicable Not Applicable Not Applicable
Canary Islands (Spain) None None Not Applicable Not Applicable Not Applicable
Cape Verde Increase in malaria cases in Praia on Sao Tiago (also known as Santiago) Island. Limited cases in other parts of Sao Tiago Island. Very Low Chloroquine PrimarilyP. falciparum For Praia: atovaquone-proguanil, doxycycline, or mefloquine
For other parts of Sao Tiago Island: mosquito avoidance
Cayman Islands (U.K.) None None Not Applicable Not Applicable Not Applicable
Central African Republic All High Chloroquine P. falciparum 85%

P. malariae, P. ovale, and P. vivax 15% combined

Atovaquone-proguanil, doxycycline, or mefloquine
Chad All High Chloroquine P. falciparum 85%

P. malariae, P. ovale, and P. vivax 15% combined

Atovaquone-proguanil, doxycycline, or mefloquine
Chile None None Not Applicable Not Applicable Not Applicable
China Present in the counties along the China-Burma (Myanmar) border in Yunnan Province. Limited transmission in Motuo county in Tibet. No malaria in areas where  most major river cruises pass. Very Low Chloroquine

Mefloquine

Primarily P. vivax

P. falciparum in Yunnan Province only.

Along China-Burma (Myanmar) border in the western part of Yunnan province: Atovaquone-proguanil or doxycycline. Motuo county in Tibet: Mosquito avoidance only.
Christmas Island (Australia) None None Not Applicable Not Applicable Not Applicable
Cocos (Keeling) Islands (Australia) None None Not Applicable Not Applicable Not Applicable
Colombia All areas at altitudes below 1,700 m (5,577 ft). None in Bogota, Cartagena, and Medellin. Low Chloroquine P. falciparum 50%

P. vivax 50%

Atovaquone-proguanil, doxycycline, or mefloquine
Comoros All No data Chloroquine Primarily P. falciparum Atovaquone-proguanil, doxycycline, or mefloquine
Congo, Republic of the (Congo-Brazzaville) All High Chloroquine P. falciparum 90%

P. ovale 5-10%

P. vivax rare

Atovaquone-proguanil, doxycycline, or mefloquine
Cook Islands (New Zealand) None None Not Applicable Not Applicable Not Applicable
Costa Rica Outbreak reported in Matina Canton in Limon Province, Sarapiqui Canton in Heredia Province, and Pital District in San Carlos Canton in Alajuela Province. Very Low Not applicable Not applicable Mosquito avoidance only
Côte d’Ivoire All High Chloroquine P. falciparum 85%

P. ovale 5-10%

P. vivax rare

Atovaquone-proguanil, doxycycline, or mefloquine
Croatia None None Not Applicable Not Applicable Not Applicable
Cuba None None Not Applicable Not Applicable Not Applicable
Cyprus Three cases of P. vivax malaria reported in UK residents who had traveled to Esentepe (also known as Agios Amvrosios) in the Kyrenia District located in Northern Cyprus. (Updated 9/21/2017) For Esentepe (also known as Agios Amvrosios) in the Kyrenia District located in Northern Cyprus: atovaquone-proguanil, chloroquine, doxycycline, primaquine, or mefloquine
Czech Republic None None Not Applicable Not Applicable Not Applicable

1. Factors that affect local malaria transmission patterns can change rapidly and from year to year, such as local weather conditions, mosquito vector density, and prevalence of infection. Information in these tables is updated regularly.

2. This estimate of risk is based on numbers of cases of malaria reported in US travelers and the estimated volume of travel to these countries. In some instances the risk may be low because the actual intensity of transmission is low in that country. In other instances, significant malaria transmission may occur only in small focal areas of the country where US travelers seldom go. Thus even though the risk for the average traveler to that country may be low, the risk for the rare traveler going to the areas with higher transmission intensity will of course be higher. For some countries that are rarely visited by US travelers, there is insufficient information to make a risk estimate.

3. Refers to P. falciparum malaria unless otherwise noted.

4. Estimates of malaria species are based on best available data from multiple sources.

5. Several medications are available for chemoprophylaxis. When deciding which drug to use, consider specific itinerary, length of trip, cost of drug, previous adverse reactions to antimalarials, drug allergies, and current medical history. All travelers should seek medical attention in the event of fever during or after return from travel to areas with malaria.

6. This risk estimate is based largely on cases occurring in US military personnel who travel for extended periods of time with unique itineraries that likely do not reflect the risk for the average US traveler.

7. Primaquine can cause hemolytic anemia in persons with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients must be screened for G6PD deficiency prior to starting primaquine.

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