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Photomicrographs Showing Histopathological Features Less Commonly Seen in Cases of HPS

Less commonly seen histopathological features in cases of HPS. Images courtesy of Sherif R. Zaki, M.D., Ph.D.

less commonly seen histopathological features in cases of HPS
  • Lung showing extensive interstitial and alveolar fibrosis. Noe the increased interstitial cellularity with numerous fibroblasts. Original magnification: x50
  • Patchy areas of alveolar septal thickening and prominent hyaline membranes. Original magnification: x50
  • Higher magnification showing typical dense laminated hyaline membranes. Original magnification: x100
  • Alveolar septum showing prominent type II pneumocyte proliferation. Original magnification: x158
  • Abundant polymorphonuclear leukocytes fill alveolar spaces with focal destruction of alveolar septa. Original magnification: x50
  • Higher power magnification showing the antraalveolar exudate composed mainly of polymorphonuclear leukocytes, red blood cells, and fibrin. Original magnification: x158

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