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TAP Clostridium difficile infection (CDI) Implementation Guide: Links to Example Resources

Disclaimer: The links in the domains below are not mutually exclusive nor do they represent an exhaustive list of all the possible resources available. Furthermore, the links presented do not constitute an endorsement of these organizations or their programs by the Centers for Disease Control and Prevention (CDC) or the federal government, and none should be inferred.

Also refer to the following guidelines:

Strategies to Prevent Clostridium difficile Infections in Acute Care Hospitals: 2014 Update

Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) [PDF – 25 pages]

Other relevant CDC guidelines.

CDI Prevention Primer Slide Set [PPT – 7.3 MB] 

I. General Infrastructure, Capacity, and Processes

Engagement of Leadership, Champions, and Staff

Empowering Staff

  • Stop the Line for Patient Safety Initiative
    Video describing an initiative that empowers staff to speak up if they see a risk to patient safety, from the U.S. Department of Veterans Affairs
  • Model Stop the Line Policy [DOC]
    Sample policy giving all hospital personnel the responsibility and authority to intervene to prevent a patient safety event, from the Minnesota Hospital Association

Staff Training and Competency Assessments

Tools for CDI Prevention Workgroup

Hand Hygiene Training and Competency Assessment

Personal Protective Equipment Training and Competency Assessment

Environmental Cleaning Training and Competency Assessment

Routine Audits


II. Antibiotic Stewardship

III. Early Detection and Isolation, Appropriate Testing

IV. Contact Precautions/Hand Hygiene

Education of Patients/Families and Visitors

V. Environmental Cleaning

VI. Laboratory Practices