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Highlighted Articles

Key Findings: Estimating the Number of People with Congenital Heart Defects Living in the United States
The journal Circulation has published a new study that estimates about 1 million children and 1.4 million adults in the United States were living with a congenital heart defect (CHD) in 2010.
(Published: July 5, 2016)

Key Findings: Newborn Screening for Critical Congenital Heart Defects Now Common Throughout the United States
In a new report in the journal, Pediatrics, CDC researchers and partners reviewed the overall effects of critical CHD screening, including costs and health outcomes (cost-effectiveness) of performing screenings, challenges at the state level for screening, and implementing screening in special settings.
(Published: April 15, 2016)

Key Findings — Use of Special Education Services among Children with CHDs
New CDC study findings in Pediatrics show that children with congenital heart defects (CHDs) received special education services more often than children without birth defects.
(Published: August 17, 2015)

Key Findings: State actions to adopt newborn screening for critical congenital heart defects
CDC’s Morbidity and Mortality Weekly Report has published a new study looking at state actions to adopt newborn screening for critical congenital heart defects (critical CHDs) using pulse oximetry – a simple, non-invasive way to measure the amount of oxygen in a newborn’s blood.
(Published: June 18, 2015)

Key Findings: Estimated Number of Infants Detected and Missed by Critical Congenital Heart Defect Screening
The journal Pediatrics has published a new study estimating the number of infants with critical congenital heart defects(critical CHDs) potentially detected or missed through universal screening for critical CHDs using pulse oximetry.
(Published: May 11, 2015)

Rapid Implementation of Statewide Mandate for Pulse Oximetry Newborn Screening to Detect Critical Congenital Heart Defects—New Jersey, 2011
New Jersey was the first state to pass a law and start a program where all licensed birthing hospitals are required to screen newborns for critical congenital heart defects. In the first three months of screening, about 98% of babies delivered were screened for critical congenital heart defects (CCHD).
(Published: July 9, 2014)

Key Findings: Prevalence of Congenital Heart Defects, Metro-Atlanta
From 1978-2005, the prevalence of more common (and less severe) congenital heart defects (CHDs) increased, while the prevalence of many severe CHDs remained stable. There are some differences in prevalence estimates between different racial/ethnic groups.
(Published: July 9, 2014)

Infant Death Due to Heart Defects
Congenital heart defects are conditions present at birth that can affect the way the heart works. They can cause lifelong disability or death. They are the most common type of birth defect, affecting nearly 40,000 births in the United States each year.
(Published: July 9, 2014)

Living with a Heart Defect
Learn about congenital heart defects and about Caden, a child living with this condition.
(Published: February 13, 2017)

Heart Defects Care for Life
Specialized care across the lifespan can help children and adults with a CHD live as healthily as possible.
(Published: February 9, 2015)

Publications

Articles of Interest

CDC and its partners conduct important research on congenital heart defects (CHDs). Listed below are a list of articles and key findings that might be of interest. Click on the links to learn more about each study.

*Articles are listed in order of date published.

Congenital Heart Defects Across the Lifespan – Estimating the Magnitude of the Affected Population in the United States.
Circulation. 2016 Jul.
Gilboa SM, Devine O, Kucik JE, Oster ME, Riehle-Colarusso T, Nembhard WN, Ping X, Correa A, Jenkins K, Marelli A.
[Read summary] [Read key findings]

Limitations, depressive symptoms, and quality of life among a population‐based sample of young adults with congenital heart defects.
Birth Defects Res Part A Clin Mol Teratol. 2016 Mar; 106(7): 580-586.
Farr SL, Oster ME, Simeone RM, Gilboa SM, Honein MA.
[Read article]

Congenital heart defects and receipt of special education services.
Pediatrics 2015
Riehle-Colarusso T, Autry A, Razzaghi H Boyle CA, Mahle WT, Van Naarden Braun K, Correa A
[Read Summary] [Read Key Findings]

Estimated number of infants detected and missed by critical congenital heart defect screening.
Pediatrics 2015 [epub ahead of print].
Ailes EC, Gilboa SM, Honein MA, Oster ME.
[Read Summary] [Read Key Findings]

Maternal cigarette smoking and congenital heart defects.
J Pediatr. 2015 Apr;166(4):801-4.
Correa A, Levis DM, Tinker SC, Cragan JD.
[Read Summary]

Long term outcomes in children with congenital heart disease: National Health Interview Survey.
J Pediatr. 2015 Jan;166(1):119-24.
Razzaghi H, Oster M, Reefhuis J.
[Read Summary]

Diabetes and Congenital Heart Defects: A Systematic Review, Meta-Analysis, and Modeling Project.
Am J Prev Med. 2015 Feb;48(2):195-204.
Simeone RM, Devine OJ, Marcinkevage JA, Gilboa SM, Razzaghi H, Bardenheier BH, Sharma AJ, Honein MA.
[Read Summary]

Role of health insurance on the survival of infants with congenital heart defects
AJPH 2014 [epub ahead of date]
Kucik JE, Cassell CH, Alverson CH, Donohue P, Tanner JP, Minkovitz CS, Correia J, Burke T, Kirby RS
[Read summary] [Read key findings]

Pediatric inpatient hospital resource use for congenital heart defects
Birth Defects Res Part A Clin Mol Teratol 2014 [epub ahead of date]
Simeone RM, Oster ME, Cassell CH, Armour BS, Gray DT, Honein MA.
[Read summary] [Read key findings]

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Late detection of critical congenital heart disease among US infants: estimation of the potential impact of proposed universal screening
JAMA Pediatrics. 2013. [epub ahead of date]
Peterson C and Ailes E, Riehle-Colarusso T, Oster ME, Olney RS, Cassell CS, Fixler DE, Carmichael SL, Shaw GM, Gilboa SM and the National Birth Defects Prevention Study.
[Read summary][Read key findings]

Costs of hospital newborn screening in New Jersey to detect critical congenital heart disease
Public Health Reports. 2013 [epub ahead of date]
Peterson C, Grosse SD, Glidewell J, Garg LF, Van Naarden Braun K, Knapp MM, Beres LM, Hinton CF, Olney RS, Cassell CH.
[Read summary][Read key findings]

Prenatal diagnosis of non-syndromic congenital heart defects
Prenatal Diagnosis. 2013 [epub ahead of print]
Ailes EC, Gilboa SM, Riehle-Colarusso T, Johnson CY, Hobbs CA, Correa A, Honein MA, National Birth Defects Prevention Study.
[Read summary] [Read key findings]

Hospitalizations, costs, and mortality among infants with critical congenital heart disease: how important is timely detection?
Birth Defects Res Part A Clin Mol Teratol 2013 [epub ahead of date]
Peterson C, Dawson A, Grosse SD, Riehle-Colarusso T, Olney RS, Tanner JP, Kirby RS, Correia JA, Watkins SM, Cassell CH.
[Read summary][Read key findings]

A public health science agenda for congenital heart defects: report from a Centers for Disease Control and Prevention expert meeting
Journal of the American Heart Association. 2013; 2: e000256
Oster ME, Riehle-Colarusso T, Simeone R, Gurvitz M, Kaltman JR, McConnell M, Rosenthal GL, Honein MA.
[Read summary] [Read key findings]

Factors Associated with Late Detection of Critical Congenital Heart Disease in Newborns
Pediatrics. 2013;132(3):e604-11.
Dawson AL, Cassell CH, Riehle-Colarusso T, Grosse SD, Tanner JP, Kirby RS, Watkins SM, Correia JA, Olney RS.
[Read summary] [Read key findings]

Cost-effectiveness of routine screening for critical congenital heart disease in US newborns.
Pediatrics. 2013; doi: 10.1542/peds.2013-0332.
Peterson C, Grosse SD, Oster ME, Olney RS, Cassell CH.
[Read summary] [Read key findings]

Results From the New Jersey Statewide Critical Congenital Heart Defects Screening Program
Pediatrics. 2013;132(2):e314-23
Garg LF, Van Naarden Braun K, Knapp MM, Knapp TM, Koppel RI, Hirsch D, Beres LM, Sweatlock J, Olney RS, Glidewell J, Hinton CF, Kemper AR.
[Read summary] [Read key findings]

Temporal Trends in Survival Among Infants with Critical Congenital Heart Defects
Pediatrics. 2013;131:e1502–e1508.
Oster ME, Lee KA, Honein MA, Colarusso T, Shin M, Correa A.
[Read summary] [Read key findings]

Rapid Implementation of Statewide Mandate for Pulse Oximetry Newborn Screening to Detect Critical Congenital Heart Defects—New Jersey, 2011
MMWR 2013; 62:292-294.
Centers for Disease Control and Prevention
[Read article] [Read key findings]

Assessment of Current Practices and Feasibility of Routine Screening for Critical Congenital Heart Defects – Georgia, 2012
Morbidity and Mortality Weekly Report. 2013;62(15):288-91.
Centers for Disease Control and Prevention
[Read article] [Read key findings]

Selected Birth Defects Data from Population-based Birth Defects Surveillance Programs in the United States, 2005-2009: Featuring Critical Congenital Heart Defects Targeted for Pulse Oximetry Screening
Birth Defects Research Part A: Clinical and Molecular Teratology. 2012;94: 970-983.
Mai CT, Riehle-Colarusso T, O’Halloran A, Cragan JD, Olney RS, Lin A, Feldkamp M, Botto LD, Rickard R, Anderka M, Ethen M, Stanton C, Erhardt J, Canfield M, for the National Birth Defects Prevention Network.
[Read summary] [Read key findings]

Letter to the Editor: Newborn screening for critical congenital heart disease: essential public health roles for birth defects monitoring programs.
Birth Defects Research Part A: Clinical and Molecular Teratology. 2012;94: 965-969.
Olney RS, Botto LD.
[Read summary][Read key finding]

Newborn Screening for Critical Congenital Heart Disease: Potential Roles of Birth Defects Surveillance Programs—United States, 2010-2011
MMWR 2012; 61: 849-853.
Centers for Disease Control and Prevention
[Read article] [Read key findings]

Maternal occupational exposure to polycyclic aromatic hydrocarbons and congenital heart defects among offspring in the national birth defects prevention study.
Birth Defects Research Part A: Clinical and Molecular Teratology. 2012 Nov;94(11):875-881.
Lupo PJ, Symanski E, Langlois PH, Lawson CC, Malik S, Gilboa SM, Lee LJ, Agopian AJ, Desrosiers TA, Waters MA, Romitti PA, Correa A, Shaw GM, Mitchell LE; National Birth Defects Prevention Study.
[Read summary]

Maternal occupational exposure to organic solvents and congenital heart defects: results from the national birth defects prevention study, 1997-2002.
Occupational and Environmental Medicine 2012;69(9):628-635.
Gilboa SM, Correa A, Desrosiers T, Lupo P, Lawson C, Riehle-Colarusso T, Stewart P, van Wijngaarden E.
[Read summary]

Congenital Heart Defects and Major Structural Noncardiac Anomalies, Atlanta, Georgia, 1968 to 2005
J Pediatr. 2011;159(1):70-78.
Miller A, Riehle-Colarusso T, Alverson CJ, Frías JL, Correa A.
[Read summary]

Associations Between Maternal Fever and Influenza and Congenital Heart Defects
J Pediatr. 2011;158(6):990-5.
Oster ME, Riehle-Colarusso T, Alverson CJ, & Correa A.
[Read summary]

Descriptive study of nonsyndromic atrioventricular septal defects in the National Birth Defects Prevention Study, 1997-2005.
Am J Med Genet A. 2011;155A(3):555-64.
Hartman RJ, Riehle-Colarusso T, Lin A, Frias JL, Patel SS, Duwe K, Correa A, Rasmussen SA, and the National Birth Defects Prevention Study.
[Read summary]

Maternal Smoking and Congenital Heart Defects in the Baltimore-Washington Infant Study
Pediatrics. 2011;127(3):e647-53.
Alverson CJ, Strickland MJ, Gilboa SM, & Correa A.
[Read summary]

Letter to the Editor: Ventricular septal defects and the National Birth Defects Prevention Study
Birth Defects Res Part A Clin Mol Teratol. 2011;91(1):66.
Rasmussen SA, Riehle-Colarusso T, Shapira SK, Honein MA, Reefhuis J, and the National Birth Defects Prevention Study.

Mortality Resulting From Congenital Heart Disease Among Children and Adults in the United States, 1999-2006.
Circulation. 2010 Nov 30;122(22):2254-63.
Gilboa SM, Salemi JL, Nembhard WN, Fixler DE, and Correa A.
[Read summary]

Racial Differences by Gestational Age in Neonatal Deaths Attributable to Congenital Heart Defects — United States, 2003–2006
Morbidity and Mortality Weekly Report (MMWR). 2010;59(37):1208-1211
CDC
[Read article]

Maternal use of bupropion and risk for congenital heart defects
Am J Obstet Gynecol. 2010; 203(1):52.e1-6.
Alwan S, Reefhuis J, Botto LD, Rasmussen SA, Correa A, Friedman JM, and the National Birth Defects Prevention Study.
[Read summary]

Long-term survival of infants with atrioventricular septal defects.
J Pediatr. 2010;156(6):994-1000.
Miller A, Siffel C, Lu C, Riehle-Colarusso T, Frías JL, Correa A.
[Read summary]

Epidemiological Studies of Congenital Heart Defects: Challenges and Opportunities
Congenital Heart Defects: From Origin to Treatment. Edited by Wyszynski DF, Graham TP, Correa-Villasenor A. Oxford University Press, New York, 2010, p. 401-414.
Honein MA, Rasmussen SA.

Health Care Costs of Congenital Heart Defects
Congenital Heart Defects: From Origin to Treatment. Edited by Wyszynski DF, Graham TP, Correa-Villasenor A. Oxford University Press, New York, 2010, p. 493-501.
Boulet SL, Grosse SD, Riehle-Colarusso T, Correa-Villasenor A.

Association Between Prepregnancy Body Mass Index and Congenital Heart Defects
American Journal of Obstetrics and Gynecology; January 2010; 202(1):51.e1-51.e10.
Gilboa SM, et al.
[Read article]

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Search a database of articles that have been published by CDC authors within the National Center on Birth Defects and Developmental Disabilities from 1990 to present.

 

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