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Case #407 - November 2015

A 50-year-old male originally from Southeast Asia was undergoing chemotherapy for squamous cell carcinoma of the lung. He was admitted one week prior with nausea, vomiting, and confusion. Pulmonary infiltrates were observed on a chest radiograph and bronchial alveolar lavage (BAL) specimens were collected for routine microbiological work-up. The following images show what was observed by the attending pathologist. Figures A and B were stained with Giemsa; Figures C and D with Papanicolaou. The objects of interest measured 500-600 micrometers in length. What is your diagnosis? Based on what criteria?

	Case407_A

Figure A

	Case407_B

Figure B

	Case407_C

Figure C

	Case407_D

Figure D

Case Answer

This was a case of disseminated strongyloidiasis caused by Strongyloides stercoralis. The images showed the infectious third instar (L3) larvae. In addition to the size, the most telling morphologic feature shown in these images was the nearly 1:1 ratio of intestine to esophagus (arrows, Figures B and C indicate the juncture between the esophagus and intestine). Another important feature is the notched tail (arrow, Figure E), which can be difficult to see unless the slide is examined at 1000x magnification with oil.

Figure B

Figure C

Figure E

More on: strongloidiasis

This case and images were kindly provided by Mercy Medical Center, Des Moines, IA

DPDx is an education resource designed for health professionals and laboratory scientists. For an overview including prevention and control visit www.cdc.gov/parasites/.

  • Page last reviewed: August 24, 2016
  • Page last updated: August 24, 2016
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